When, during the early centuries of the Christian era, the traditions of Greece found a new home in lower Egypt, and especially in Alexandria, they were profoundly influenced by the still more ancient philosophy of the East. We have already remarked this in the case of another science, that of physiognomy, but the same influence may also be traced in the modification it brought to the notions of primitive chemistry. The Chaldæans and Persians had long believed that the heavens influenced the earth, and were capable of producing strange effects in the lower spheres of being.[109] Their wise men considered that an individual connection could be established between the stars and the elements, the planets and the metals. It was in contact with this new doctrine and under its influence that there arose the hope, soon hardening into a settled belief, that the rules of art might be sufficient to effect an actual transmutation of the baser into the nobler metals, of copper into gold, and of tin or lead into silver. This opinion must have been immensely heightened, and its authority reinforced, by the secrecy with which the receipts for alloying metals were guarded. These were handed down orally from father to son; were not committed to writing till a comparatively late period, and even then remained for the most part the cherished treasures of temple guilds. On the well-known principle of the proverb, ‘Omne ignotum pro magnifico’ this secrecy tended to confirm the impression that, however much had been communicated, more remained untold, to await discovery by the patient and undaunted chemist. The Therapeutæ or Essenes were among the earliest representatives of this new tendency, as appears from the testimony of Josephus,[110] who describes them as not only devoted to ancient writings, but eager to investigate the properties of minerals. The chief object of their inquiries, the maintenance of health by medicines thus derived from the vegetable and mineral kingdoms, is not only an early instance of the connection between chemistry and pharmacy, but is remarkable as the probable starting-point of the search for the elixir of life: that other and nobler dream which so much of the enthusiastic energy of the mediæval alchemists was spent to realise.