Some years prior to this period (1778) Mrs. Thrale's mind and character had undergone a succession of the most trying ordeals, and was tempered and improved, without being hardened, by them. In allusion to what she suffered in child-bearing, she said later in life that she had nine times undergone the sentence of a convict,--confinement with hard labour. Child after child died at the age when the bereavement is most affecting to a mother. Her husband's health kept her in a constant state of apprehension for his life, and his affairs became embarrassed to the very verge of bankruptcy. So long as they remained prosperous, he insisted on her not meddling with them in any way, and even required her to keep to her drawing-room and leave the conduct of their domestic establishment to the butler and housekeeper. But when (from circumstances detailed in the "Autobiography") his fortune was seriously endangered, he wisely and gladly availed himself of her prudence and energy, and was saved by so doing. I have now before me a collection of autograph letters from her to Mr. Perkins, then manager and afterwards one of the proprietors of the brewery, from which it appears that she paid the most minute attention to the business, besides undertaking the superintendence of her own hereditary estate in Wales. On September 28, 1773, she writes to Mr. Perkins, who was on a commercial journey:-- "Mr. Thrale is still upon his little tour; I opened a letter from you at the counting-house this morning, and am sorry to find you have so much trouble with Grant and his affairs. How glad I shall be to hear that matter is settled at all to your satisfaction. His letter and remittance came while I was there to-day.... Careless, of the 'Blue Posts,' has turned refractory, and applied to Hoare's people, who have sent him in their beer. I called on him to-day, however, and by dint of an unwearied solicitation, (for I kept him at the coach side a full half-hour) I got his order for six butts more as the final trial." Examples of fine ladies pressing tradesmen for their votes with compromising importunity are far from rare, but it would be difficult to find a parallel for Johnson's Hetty doing duty as a commercial traveller. She was simultaneously obliged to anticipate the electioneering exploits of the Duchess of Devonshire and Mrs. Crewe; and in after life, having occasion to pass through Southwark, she expresses her astonishment at no longer recognising a place, every hole and corner of which she had three times visited as a canvasser.