Because there is a great Difference made between the fixed and wandering Gout, I shall observe a few Things thereon. As to the wandering Gout, it is observable that the Mucilage of the Glands is often very differently affected from the viscid and saline Particles of the Blood; sometimes these Particles are mixed in different Quantities with the Mucilage, neither have the Salts at all Times the same Degree of Volatility or Fixity; so that the Mucilage may at some Times be only lightly infected, and the Infection be more Volatile, and consequently it may easily move from one Joint to another, or attack many Joints at a Time. The Points of the Salts are in a Manner lixiviated, become more volatilized, and of Consequence are with more ease protruded from the Blood into the Glands, and render the mucilaginous Juices sharper; whence the nervous Membranes are irritated and distended, and the gouty Pain generated. SECT. 7. The Reason why this morbid Matter is not long fixed in a Place, but is apt to wander from one Joint to another, I take to be this: These saline volatile Particles, when their intestine Motions are increased, are very easily dissipated, either through the Pores of the Skin in sensible Transpiration and Sweat, or by insensible Perspiration, and so the Pain ceases; other Glands, whose Pores are more open to receive this acrid volatile Matter, are for the like Reasons infected, the same Tragedy repeated, and the Particles in like manner dissipated. This is the Reason why the Pains in the Gout are not fixed and permanent, but rather wandring and uncertain, the morbid Particles being attenuated, and pushing to get forth by the Methods now mentioned, vellicate the Nerves in various Directions. It may be further considered, that when by the smallness of the Pores or glandulous Vessels, or any other Disposition, the morbifick Matter cannot be separated from them in sufficient Quantity, and the Secretion once begun is stopped, it recurs to other Glands of the same kind, and thus the morbid Matter is suddenly translated from one Joint to another, and from one Sett of Glands to others, so as to produce this Effect. SECT. 8.