Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
The fairly extensive study that has been made of the incidence of B.
influenzæ in normal men and in cases of measles has clearly demonstrated
that the proportion of carriers found in any group depends upon the
prevalence of influenza in the group studied and that with the progress
of the epidemic the percentage of carriers has steadily increased. When
one considers that the opportunity for the dissemination of B. influenzæ
by contact infection is almost unlimited during an epidemic of the
proportions of that which has swept over the country, this is not at all
surprising. That such a large number of normal individuals became
carriers of B. influenzæ during the epidemic would seem to be sufficient
evidence that actual dissemination does occur and to controvert the
theory that in actual cases of influenza, conditions are established in
the respiratory tract whereby B. influenzæ, always present in small
numbers, is enabled to “grow out” and become the predominant organism.
From a consideration of all the observations made as to the incidence of
B. influenzæ in various conditions it would appear that the carrier
condition is quite analogous to that found with many other bacteria, and
may be divided into three groups: (_a_) acute carriers, those having
influenza, (_b_) contact carriers, those who during epidemic times
become temporary carriers of the organism without contracting the
disease, and (_c_) chronic carriers, the relatively small number of
normal individuals or those with chronic respiratory conditions who
carry B. influenzæ over long periods of time. From the facts at hand
this would seem to be the most probable explanation of the conditions
found. It is certainly true that the established presence of
pneumococcus, B. diphtheriæ, meningococcus and many other organisms in a
varying proportion of normal individuals is not regarded as sufficient
evidence to exclude them as the etiologic agents of the diseases which
they cause.
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