In the early part of the formation, injection of a five or ten per cent. carbolic acid solution, or covering the whole area with a twenty-five per cent. ichthyol ointment, may be employed. When it has broken down the pus may be drawn out with a cupping-glass, and carbolized glycerine or carbolized water introduced into each opening, and the ichthyol ointment superimposed. If the whole part has sloughed, it should be removed as rapidly as possible, and antiseptic dressings used. Or, if its progress is slow, and grave systemic disturbance be present, the whole part may be incised and curetted, and then treated antiseptically. Mild exposure to the _x_-rays is also to be commended. #Pustula Maligna.# (_Synonyms:_ Anthrax; Malignant Pustule.) #What is malignant pustule?# Malignant pustule is a furuncle- or carbuncle-like lesion resulting from inoculation of the virus generated in animals suffering from splenic fever, or "charbon," and is accompanied by constitutional symptoms of more or less gravity. A fatal termination is not unusual. #What is the cause of pustula maligna?# The disease is due to the presence of the bacillus anthracis. #What is the treatment of malignant pustule?# Early excision or destruction with caustic potash, with subsequent antiseptic dressings; and internally the free use of stimulants and tonics. #Post-mortem Pustule.# (_Synonym:_ Dissection Wound.) #Describe post-mortem pustule.# Post-mortem pustule develops at the point of inoculation, beginning as an itchy red spot, becoming vesico-pustular, and later pustular, with usually a broad inflammatory base, and accompanied with more or less pain and redness and not infrequently lymphangitis, erysipelatous swelling, and slight or severe sympathetic constitutional disturbance. #What is the treatment of post-mortem pustule?# Treatment consists in opening the pustule and thorough cauterization, and the subsequent use of antiseptic applications or dressings. _Internally_ quinia and stimulants if indicated. #Framb[oe]sia.# (_Synonyms:_ Yaws; Pian.) #Describe framb[oe]sia.# Framb[oe]sia is an endemic, contagious disease met with in tropical countries, characterized by the appearance of variously-sized papules, tubercles, and tumors, which, when developed, resemble currants and small raspberries, and finally break down and ulcerate. It is accompanied by constitutional symptoms of variable severity. Hygienic measures, good food, tonics, and antiseptic and stimulating applications are curative. #Verruga Peruana.# (_Synonyms:_ Peruvian Warts; Carrion's Disease; Oroya Fever.) #Describe verruga peruana.#