Though happy in the affection of his wife and Mrs. Bowes, Knox, at this time, needed more of feminine society. On November 19, 1556, he wrote to his friend, Mrs. Locke, wife of a Cheapside merchant: "You write that your desire is earnest to see me. Dear sister, if I should express the thirst and languor which I have had for your presence, I should appear to pass measure. . . . Your presence is so dear to me that if the charge of this little flock . . . did not impede me, my presence should anticipate my letter." Thus Knox was ready to brave the fires of Smithfield, or, perhaps, forgot them for the moment in his affection for Mrs. Locke. He writes to no other woman in this fervid strain. On May 8, 1557, Mrs. Locke with her son and daughter (who died after her journey), joined Knox at Geneva. {73} He was soon to be involved in Scottish affairs. After his departure from his country, omens and prodigies had ensued. A comet appeared in November-December 1556. Next year some corn-stacks were destroyed by lightning. Worse, a calf with two heads was born, and was exhibited as a warning to Mary of Guise by Robert Ormistoun. The idolatress merely sneered, and said "it was but a common thing." Such a woman was incorrigible. Mary of Guise is always blamed for endangering Scotland in the interests of her family, the Guises of the House of Lorraine. In fact, so far as she tried to make Scotland a province of France, she was serving the ambition of Henri II. It could not be foreseen, in 1555, that Henri II. would be slain in 1559, leaving the two kingdoms in the hands of Francis II. and Mary Stuart, who were so young, that they would inevitably be ruled by the Queen's uncles of the House of Lorraine. Shortly before Knox arrived in Scotland in 1555, the Duc de Guise had advised the Regent to "use sweetness and moderation," as better than "extremity and rigour"; advice which she acted on gladly.