Observations on the Operation and Use of Mercury in the Venereal DiseaseDuncan, Andrew
History
Observations on the Operation and Use of Mercury in the Venereal Disease
Duncan, Andrew
Mercury -- Therapeutic use -- Early works to 1800; Sexually transmitted diseases -- Early works to 1800
This gummous solution is, in the table of mercurials, reduced to the
same general head with the two preparations last treated of; the mercury
in this case likewise being rendered active by division from triture.
Although the use of this preparation is but a late proposal, yet, since
its introduction, it has been a good deal employed, and the facts which
may be had with regard to it cannot be alledged to be few. That general
observations, however, may, with justice, be made, numerous facts are
requisite; and perhaps what can as yet be had on this subject are still
an insufficient foundation for any certain conclusions.
It may, however, with regard to this medicine, be confidently asserted,
that the opinions upon which its superior efficacy is founded are
without foundation. It is a mistake to suppose, that any peculiar
affinity, or specific elective attraction, takes place betwixt mercury
and vegetable mucilage. And mercury with gum, as well as in other forms,
if, from triture, it be rendered sufficiently active, and if it be
introduced into the system in sufficient quantity, will also excite
salivation. This preparation, then, is still to be considered as, in a
great measure, on the same footing with the two others already
mentioned.
But, united with vegetable mucilage, mercury seems to act less upon the
intestines than the mercurial pill. This is probably to be referred to
the viscidity of the substance with which the mercury is here combined.
Vegetable gum possesses a remarkable power of sheathing and defending
those parts to which it is applied against acrimony of any kind.
This preparation, taken in what would seem an equal proportion with the
mercurial pill, shows a less powerful action on the system, both in its
effects on the excretions, and in its influence on the morbid symptoms.
This diminution of action may perhaps, in some degree, be accounted for
from the mercury being less readily absorbed into the system, after
entering the alimentary canal, in consequence of the viscidity of the
gum with which it is united. But as vegetable mucilage, when taken by
itself, is observed to diminish the action of mercury, in whatever way
it be introduced into the system, this effect must be principally
accounted for from some other cause. Probably it depends upon the
influence of the mucilage, after having entered the system, in defending
the excretories against the violence of the stimulus from the mercury.
This form may, upon the whole, be esteemed, although not a powerful,
yet, in many cases, an useful preparation. It is chiefly preferable to
other mercurials in those recent cases of _lues venerea_ where a weak
preparation will answer the purpose; and where, at the same time, it
seems most adviseable that the mercury should be slowly introduced into
the system.
Public-domain text, read in full here on John Shaqi.
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