“Jamalli Khan, a Mahommedan, aged twenty-four, admitted into the hospital on the 25th of December, 1875. He is a resident of Calcutta, and an ordinary labourer (coolie). He states that he had been suffering from ‘fever’ for the last two months, at first intermittent in character, but for the last seven days more or less continued. He is much emaciated and reduced in strength. Complains of pain on pressure over the liver and spleen; the latter can be felt much enlarged, reaching downwards to nearly the level of the umbilicus; the lower border of the liver, however, can only just be felt below the ribs. Temperature on evening of admission 101° F. Conjunctivæ are anæmic, but not jaundiced. Has also a little bronchitis. The fever continued with slight remissions for ten days (January 4th, 1876), the highest diurnal temperature (in the afternoon) varying from 103° to 104° F.; it then abated, but dysentery set in. He began to pass six or eight stools in the twenty-four hours, attended with much griping, and containing varying quantities of blood-tinged, gelatinous mucus. These became more frequent, in spite of treatment, during the next three days, and on the 8th of January he was manifestly sinking; passed his evacuations into the bedclothes, became cold and collapsed, and died in this state that same evening. “A post-mortem examination was made on the following morning, thirteen hours after death. All the organs of the body were found more or less anæmic, but exhibited nothing remarkable with the following exceptions. The lungs towards their posterior margins and bases were dark, but still spongy and crepitant. The spleen was found greatly enlarged, heavy; capsule tense and stretched; substance soft, reddish brown, irregularly pigmented; weight 1 lb. 13 oz. The liver was of about normal size; its surfaces smooth, the capsule slightly hazy looking. Hepatic substance firm, but abnormally dark, and the bile-ducts particularly prominent and thickened. Numbers of small distomata escaped from the incisions made into the organ, and could be seen protruding from the dilated biliary canals. The gall-bladder was filled with thick greenish-yellow bile, measuring about an ounce and a half, but containing no parasites, and no ova even could be detected on microscopical examination of this bile and of scrapings from the lining membrane of the gall-bladder. The cystic duct was free from obstruction. The condition of the common choledic duct could not so well be ascertained, as the liver had been removed from the abdominal cavity before anything extraordinary had been detected in its condition, but, so far as it could be examined, it was found patent; the duodenal mucous membrane was well bile-stained, and there was evidence of biliary colouring matter in the fæcal contents of the bowels. On carefully dissecting out, and then laying open, the biliary ducts in a portion of the right lobe of the liver (the rest