_Symptoms._ Both plants are emetic and dangerously purgative, causing irritant and narcotic symptoms. Veterinary observation has shown that the poison is cumulative, and that it is usually after the weed has formed part of the food for 7, 8, or 10 days that symptoms first appear. In the case recorded by Blackhurst (see above) the cows suffered from inflammation of the digestive tract, with severe purging and loss of blood. The secretion of milk entirely stopped. One cow died, but three recovered in about four days. The fifth was not convalescent for three weeks and then had a permanently curved and injured neck, the muscles being subsequently found rich in fibrous tissue, and the last three joints partially anchylosed. Rabbits were tested by feeding two on the leaves, two on the stems and roots, and two on the ground seeds mixed with oatmeal; the first two were unaffected, but the other four died in a few hours, showing drowsiness and suffering, while the post-mortem showed gastritis. The digestive and urinary tracts are affected. There is indigestion with slight bloating, then colic of varying intensity, and at first diarrhœa which may give place later to constipation; hæmaturia; micturition is frequent, painful, and the urine is blackish and bloody; dullness, weakness, loss of appetite and refusal of food; the heart beats very strongly, the pulse is rapid, and the mucous membrane of the eye is reddish-yellow in colour. There is no modification of respiration (Cornevin). According to Müller, however, the symptoms at _first_ include constipation and _later_ severe and bloody diarrhœa. In cattle Pott states that _M. annua_ causes inflammation of the stomach and intestines, bloody urine, paralysis of bladder, fœtid diarrhœa, abortion, and bluish coloured milk deficient in fat. Müller states that there is occasionally blood in the milk. According to Lander there is in cows excessive bloody purgation, cessation of lactation, temperature 105° F., pulse 90, and increased respiration. The illness is protracted over several weeks, the animals being comatose after the first symptoms. REFERENCES. 73, 81, 112, 130, 146, 170, 190, 205, 213, 255. =Box= (_Buxus sempervirens_ L.). Farm live-stock may occasionally have the opportunity of browsing on box, or clippings may be thrown to them with other green herbage from gardens. Care should be taken that clippings are otherwise disposed of. All parts of the plant are bitter and have been proved to be poisonous. The bitter taste tends to prevent animals eating sufficient of the plant to cause serious injury. Pigs have died a day after eating the leaves. Horses also were killed by eating 750 grammes (1·6 lb.) of the foliage.