Of all the experiments which have yet been undertaken with a view to trace the course of alcohol through the human system, the most important were those made in Paris a few years ago by Professors Lallemand, Perrin, and Duroy, distinguished physicians and chemists. Frenchmen have a way of co-operating with one another, both in the investigation of scientific questions and in the production of literature, which is creditable to their civilization and beneficial to the world. The experiments conducted by these gentlemen produced the remarkable effect of causing the editor of a leading periodical to confess to the public that he was not infallible. In 1855 the Westminster Review contained an article by Mr. Lewes, in which the teetotal side of these questions was effectively ridiculed; but, in 1861, the same periodical reviewed the work of the French professors just named, and honored itself by appending a note in which it said: "Since the date of our former article, scientific research has brought to light important facts which necessarily modify the opinions we then expressed concerning the _rôle_ of alcohol in the animal body." Those facts were revealed or indicated in the experiments of Messrs. Lallemand, Perrin, and Duroy. Ether and chloroform,--their mode of operation; why and how they render the living body insensible to pain under the surgeon's knife; what becomes of them after they have performed that office,--these were the points which engaged their attention, and in the investigation of which they spent several years. They were rewarded, at length, with the success due to patience and ingenuity. By the aid of ingenious apparatus, after experiments almost numberless, they felt themselves in a position to demonstrate, that, when ether is inhaled, it is immediately absorbed by the blood, and by the blood is conveyed to the brain. If a surgeon were to commit such a breach of professional etiquette as to cut off a patient's head at the moment of complete insensibility, he would be able to distil from the brain a great quantity of ether. But it is not usual to take that liberty except with dogs. The inhalation, therefore, proceeds until the surgical operation is finished, when the handkerchief is withdrawn from the patient's face, and he is left to regain his senses. What happens then? What becomes of the ether? These learned Frenchmen discovered that most of it goes out of the body by the road it came in at,--the lungs. It was breathed in; it is breathed out. The rest escapes by other channels of egress; it all escapes, and it escapes unchanged! That is the point: it escapes without having _left_ anything in the system. All that can be said of it is, that it entered the body, created morbid conditions in the body, and then left the body. It cost these patient men years to arrive at this result; but any one who has ever had charge of a patient that has been rendered insensible by ether will find little difficulty in believing it.