Notwithstanding their agility and spasmodic activity, the muscular system of criminals is generally feeble. Such few observations as have yet been made show that muscular anomalies are found with remarkable frequency. Thus the investigations of Guerra on the bodies of 12 normal persons and 18 criminals, showed 11 anomalous muscular conditions in the latter as against 5 in the former. Lacassagne some years ago pointed out the remarkable length of the extended arms (_la grande envergure_). Although many observers refer to this peculiarity, and in many isolated cases it is marked and doubtless connected with the agility of criminals, as among some lower races and the apes, I am not acquainted with any extended series of observations in which criminals and normal persons are fairly compared in this respect. Marro’s series, although the normal persons are in too small number, as he himself points out, is as reliable as any, and does not in the average show any preponderance of long-armed individuals among criminals. There is, however, reason to believe that individuals with exceptionally long arms are more often met with among criminals. “Among the inmates of the Elmira Reformatory,” remarks Dr. H. Wey, “the greatest physical deficiency and least resistive power is found in the respiratory apparatus. Pigeon-breasts, imperfectly developed chests, and stooping shoulders abound. During a period of eight years, with 26 deaths, 13, or 50 per cent., were from diseases of the chest, not including affections of the heart.” In his answers to my Questions a prison surgeon remarks, “Many men have large nipples and large well-marked areolæ. This is often very remarkable.” I am not aware that this has been noticed by any other observer, and the point deserves further examination. Heart disease is common among criminals. Out of 54 examined by Flesch, 20 per cent. died of heart disease, 50 per cent. showed affections of the heart. Valvular insufficiency and cardiac atrophy seem to be remarkably prevalent. Penta found endarteritis and atheroma in 82 of his 184 instinctive criminals, _i.e._ 44 per cent., although many of them were young. The condition, he says, was diffused and pronounced; 20 of these 82 showed aortic insufficiency. It may be noted that arterial anomalies are extremely frequent. Thus Guerra found 14 arterial anomalies in his 18 criminals as against 4 in his 12 normal persons. Heart disease is also common among the insane. Its tendency to produce mental alterations has often been noted; pride, egotism, and an inclination to violence are found, especially (according to Witkowski) among those affected with ventricular hypertrophy; with aortic disease, neurotic and hysterical states; with mitral disease, melancholy and attacks of violence. This is not surprising when we remember the intimate connection that subsists normally between the heart and the brain, the vascular system forming, as it were, the basis of the brain.