Finally, upon the general introduction of printing, physician, apothecary, mountebank, speculator, all seized upon the "power of the press," to more extensively introduce their "wonderful discoveries." When you notice the name--and, O, ye gods, such names as are patched up to attract your attention!--to a new medicine, systematically and extensively advertised in every paper you chance to pick up, you wonder how any profit can accrue to the manufacturer of the compound after paying such enormous prices as column upon column in a thousand newspapers must necessarily cost. "If the articles cost anything at the outset," you go on to philosophize, "how can the manufacturers or proprietors make enough profit to pay for this colossal advertising?" The solution of the problem is embodied in your inquiry. They cost nothing, or as near to nothing as possible for worthless trash to cost. This is the secret of the fortunes made in advertised medicines. When we _know_ the complete worthlessness of the majority of the articles that are placed before the public,--yea, their more than worthlessness, for they are, many of them, highly injurious to the user,--the fact of their enormous consumption is truly astonishing. The drug-swallowing public has grown lean and poor in proportion as the manufacturers and venders of these villanous compounds have grown fat and wealthy. Said the proprietor of "Coe's Cough Balsam" and "Dyspepsia Cure" to the author, "If you have got a _good_ medicine, one of value, don't put it before the public. I can advertise _dish water_, and sell it, just as well as an article of merit. It is all in the advertising." As the above preparations were advertised on every board fence, and in every newspaper in New England at least, did his assertion imply that those articles were mere "_dish water_"? "SPALDING'S GLUE." I was informed by a Mr. Johnston, who engineered the advertising of the preparation, that it cost but one eighth of a cent per bottle. If you want to make a liquid glue, dissolve a quantity of common glue in water at nearly boiling point, say one pound of glue to a gallon of water; add an ounce or less of nitric acid to hold it in solution, and bottle. The more glue, the stronger the preparation. The pain-killers and liniments are the most costly, on account of the alcohol necessary to their manufacture; and, in fact, the principal item of expense in all liquid medical articles put up for public sale, is in the alcohol essential to their preservation against the extremes of heat and cold to which they may be subjected. SOURED SWILL.