persons of the second class, right-handed but using the left as the guiding hand with the axe, seventeen found the right hand the more sensitive, and fifteen the left, while twenty-four felt no difference. Of eighteen of the third class, six found the right hand the more sensitive, seven the left hand, and five could detect no difference. Another case was that of a lady, decidedly left-handed, who writes, sews, and apparently does nearly everything with her left hand. She tried at three temperatures, viz. 5°, 30°, and 48° centigrade. In the first case she pronounced the left hand to be undoubtedly colder, in the second she observed no difference, and in the third, the left hand was undoubtedly warmer. Another lady, also habitually using her needle in the left hand, and otherwise instinctively reverting to that hand in all operations requiring delicate or skilful manipulation, repeated the same experiment more than once at my request; but could not detect any difference in the sensitiveness of either hand. The results thus stated were all arrived at with great care. It is manifest that they fail to confirm the statement set forth in the _Physiology of Common Life_, or to point to any uniformity in the relative sensitiveness of the right and left hands. In so far as either hand may prove to be more sensitive to heat than the other, it is probably due to the constant exertion of the one hand rendering it less sensitive to changes of temperature. Yet even this is doubtful. Two carpenters chanced to be at work in the College building while the above experiments were in progress. They were both right-handed workmen; yet, contrary to expectation, on being subjected to the test, they both pronounced the right hand to be more sensitive to heat. The statement of Mr. Lewes is so definite that the subject may be deserving of more extended experiment under other conditions. Any widely manifested difference in the sensitiveness of one of the hands, apart from its habitual use in all ordinary manipulation, and especially among uncultured races, would assuredly seem to indicate some congenital distinction leading to the preferential use of the right hand. But whatever may be the source of this preference, the difference between the two hands is not so great as to defy the influence of education; as is seen in the case of those who, even late in life, through any injury or loss of the right hand, have been compelled to resort to the less dexterous one. Of the occurrence of individual examples of left-handedness the proofs are ample, seemingly from earliest glimpses of life to the present time; and it would even appear that, in so far as the small yet definite amount of evidence of the relative percentage of the left-handed enables us to judge, it differs little now from what it did at the dawn of definite history.