_Boston, 1832_. DEAR HENRY,--You have requested me to give you some information concerning the science and literature of the United States, which have been so often the subjects of ridicule and derision in the critical reviews and other literary journals of our country. I take great pleasure in complying with this request, as far as my limited opportunities have enabled me to judge of their condition. I have read almost every American work of any merit I could obtain, and mingled with some of their men of science and letters, for the purpose of being directed in my researches, and of acquiring from personal observation, a better knowledge of their living authors. In science, perhaps, for so young and growing a nation, its progress has been as steady and rapid as could reasonably have been expected. In the exact and physical sciences, there are some who, though they have not greatly enlarged their circle, are nevertheless profoundly versed in them, and who would not be ranked below the best in Europe. In chemistry, mineralogy, and botany, several have acquired great distinction, and these sciences are becoming daily more popular and more generally cultivated. Many of the young of both sexes attend occasional and regular lectures on each, but especially on the first and last, and it is not rare to meet with females conversant to a certain degree with both. In the northern cities, public lectures are delivered on various branches of science, which are attended by both sexes. There are at present several scientific journals published in the United States, which are said to be pretty generally patronized, and two or three scientific associations, whose transactions have been given to the public. Of the former, the most meritorious are--Silliman's Journal of Science, the Franklin Quarterly Journal, Chapman's and some other medical journals, and two or three law journals. Of the philosophical transactions I can say but little. I have merely glanced over those of the American Philosophical Society, the American Academy of Arts and Sciences, and the Literary and Philosophical Society of New York, but that glance has not impressed me very favorably with the genius or learning of their members. Some few papers are indeed valuable, and exhibit considerable research and erudition, but they appear to be deficient in originality, depth and lucidness. I have, however, never been very partial to these associations. The amount of their contributions to science or literature has never been so great as to render their formation desirable in my eye, and certainly they are not to be compared with the individual labors of those great luminaries who have shed such radiance over the paths of science. Scientific men here have published from time to time the result of their labors in the different physical sciences, to the cultivation of which they have devoted a large portion of their lives. The botanical works of Bigelow, Nutall,