----+--------+-------+-------------+--------------+------------------- 310| 880 | 0.2 |2 days(1) |About |Belgian; oats. | | | | 2.5 days(1)| 311| 650 | .2 | |Survived | Do. 312| 740 | .2 |40 minutes |4.5 hours |Maltese; oats. 78| 659 | .257|15 minutes |Survived |Yellow and white; | | | | | oats. 75| 842 | .2 | do. | do. |Gray and white. 74| 692 | .2 | do. | do. | 317| 635 | .252|1 hour |About 2 hours |Belgian; oats. | | | 25 minutes| | 323| 820 | .25 |1 hour |Survived |White; oats. | | | 15 minutes| | ----+--------+-------+-------------+--------------+------------------- (1) Not due to caffein. INTRAMUSCULAR INJECTION. Well-fed rabbits, which received a diet exclusively of oats, were used for these experiments. The injections were made into the lumbar or into the gluteal muscles. SERIES A. In this series the caffein was injected into the gluteal muscles. _Rabbit 284. Brown and white, female. Weight, 1,100 grams._ December 14: 2 p. m., 11 cc 2 per cent caffein injected into the gluteal muscles (0.2 gram per kilo), under observation until 5 p. m., had frequent convulsions; at 5 p. m. in a comatose condition. Rabbit was found dead the next morning. _Rabbit 286, white and black, female. Weight, 1,315 grams._ December 15: 2.30 p. m., 13 cc 2 per cent caffein injected into the gluteal muscles (0.1977 gram per kilo), tremors and increased reflexes observed during the next two hours, but no other symptoms. December 17: Rabbit alive. _Rabbit 285, yellow and white, female. Weight, 1,385 grams._ December 14: 10.15 a. m., 14 cc 2 per cent caffein injected into the gluteal muscles (0.2 gram per kilo), general tremors, but no convulsions observed. Rabbit survived. December 17: Rabbit still alive. _Rabbit 287. Belgian hare, female. Weight, 1,140 grams._ December 15: 2.15 p. m., 11 cc of 2 per cent caffein injected into the gluteal muscles; 2.30 p. m., tonic contractions of posterior limbs. Paralysis and death at 2.40 p. m. SERIES B. In series B the caffein was injected into the lumbar muscles. _Rabbit 307. Belgian hare, female. Weight, 1,175 grams._ February 16: 11.05 a. m., 8 cc 2 per cent caffein injected (0.136 gram per kilo) into the lumbar muscles; under observation until 4 p. m., no symptoms; 4 p. m., allowed to walk on the floor; after walking a short distance loss of coordination and paralysis of posterior extremities; 5.20 p. m., found dead. _Rabbit 306. Belgian hare, female. Weight, 1,860 grams._ February 16: 11 a. m., 12.5 cc 2 per cent caffein injected into the lumbar muscles; 12 noon, no symptoms; 2 p. m., walked about 10 feet, exhaustion and paralysis; 3 p. m. found dead.