Again, in 190 cases of acute and subacute rheumatism the average duration, under salicyl remedies, of pyrexia was 5.5 days and of joint disease, 5.3 days (Warner[133]); in 156 cases at St. George's Hospital the average duration of pyrexia was 3.66 days, of pain 4 days (Owen[134]); in 82 at the Middlesex the average duration of pyrexia was 5 days, of pain 5.6 days (Coupland[135]); and in 55 at the Westminster the average duration of pyrexia was 7 days, of pain 7.25 days[136]--that is, a general average duration in the whole series for the pain and pyrexia of 5.4 days. [Footnote 133: _Ibid._, p. 1080.] [Footnote 134: _Ibid._, p. 1081.] [Footnote 135: _Ibid._, i., 1882, 10.] [Footnote 136: _Ibid._, ii., 1881, p. 1080.] Further, 36 per cent. of Fagge's cases and 58 per cent. of Greenhow's were relieved of both the above symptoms on the fourth day; 24.8 per cent. of Fagge's and 50 per cent. of Greenhow's on the third day; and 13.5 per cent. of Fagge's and 26.6 per cent. of Greenhow's on the second day. In Clouston's 27 cases, treated in private, 66.6 per cent. were free from pain and 59 per cent. from fever within three days, and 85.2 per cent. were devoid of pain and 72.7 per cent. of fever within four days.[137] Finally, all who have had much experience of this method of treating acute rheumatism will agree that the first or second dose frequently relieves the articular pains like a charm, and the local swelling then frequently subsides in from sixteen to forty-eight hours. [Footnote 137: _The Practitioner_, i., 1882.]