[41] Dr. _Pringle_, in the _fourth Edition of his Observations_, just published, in treating of the third or last Stage of the Dysentery, remarks, that this is the Time for Astringents, which ought not to be given sooner, or at least very sparingly. And he tells us, that, in the former Editions of his Work, he mentioned those Compositions which he had most frequently used, but that he had now laid most of them aside; and at present trusts to Vomits, and to a Milk Diet, for the perfect Cure. He says, “Whenever therefore the Patient is in this State, and especially when his Pulse is quick, and he complains of inward Heat, I began with giving him a Scruple of Ipecacuana; and the next Day I put him upon the Milk-Diet; which I continue till all the hectic Symptoms are gone, and till the Bowels have recovered their Tone. During this Course I have seldom had Occasion for any other Medicine, excepting the Chalk Julep mentioned before, which I use for correcting that strong Acid so incident to relaxed Stomachs. Sometimes also I add an Opiate to procure Rest at Night; but after a few Days these are likewise laid aside. All that I require (which indeed is often hard to obtain) is a strict Perseverance in the low Diet: and now and then a Repetition of the Vomit, upon any new Disorder of the Stomach, or great Laxity of the Bowels. “Whilst the Patient continues in this Course, I forbid all animal Food and fermented Liquors; and besides Milk, I allow only the Preparations of Grain, Sago and Salop.” See Part iii. ch. vi. p. 289, 290. A Spoonful of the _mixtura fracastorii_, taken after every loose Stool; and an anodyne Draught at Night, had a good Effect with some--Repeated Doses of the _philonium Londinense_ answered better with others, who were low, and required a Remedy that was warm and cordial--And others found more Benefit from the Mindereri Draughts, with Mithridate, or the _confectio cardiaca_, or the Theriac anodyne Boluses. The _mixtura Campechensis_, both alone and with _tinctura thebaica_, checked the Purging, and gave Relief sometimes; and the Addition of some of the Extract of Bark and Tincture of Cinnamon, seemed to encrease its Efficacy in one or two old Cases, at _Bremen_; but it afterwards occasioned such Sickness, that we did not continue its Use. In other inveterate Dysenteries, where we thought that a strong Astringent was wanted, we added a small Proportion of Allum to the _Campechense_ Julep, which on first using seemed to be serviceable; but at other Times it occasioned a Tenesmus and Gripes; and therefore we were obliged to be very cautious how we used it. Equal Parts of the _electuarium diascordii_ and _electuarium corticis_, taken in the Quantity of a Drachm twice or thrice a Day, was of Use in many old Fluxes[42], though it made other Patients so sick, that they were obliged to lay it aside.