In spite of all this, long habit has secured to these pernicious customs a sort of prescriptive right. The distress consequent upon them, increases in proportion as the reactive powers of the organism decrease, which is more particularly the case in the present generation. The suppression of these abuses has never been more necessary than in our age. Indeed, the old proverb is again verified: "Where need is greatest, there help is nearest." The world is not only indebted to Hahnemann for a knowledge, but also for a natural corrective of this serious abuse. His provings on healthy persons show this beyond a doubt. Few men, if their attention has once been directed to this abuse, will feel disposed to deny its extent. Nor has a favorable change in this respect been looked for in vain, since homœopathy has now, for half a century at least, shown the uselessness of all regular methods of purgation, and the superiority of the means with which this new system accomplishes most effectually all that those pernicious methods promised to do. It should be considered a duty by every physician, to be acquainted with the new means of cure. The continued use of purgatives should be considered a crime against health. They will soon cease to exist as regular means of treatment, and their pernicious consequences will no longer have to be relieved by remedial means. But until their use is abolished, we shall have to counteract them by adequate means of cure, more particularly the abnormal irritation and the paralytic debility, which are the most common consequences of the abuse of cathartics. It is a most fortunate thing that we have in Apis one of the most reliable means of removing the evil effects of cathartic medicines. A single globule of Apis 30 is sufficient to this end. It is best to use it as follows: dissolve the globule in five tablespoonfuls of water by shaking the mixture well in a well closed vial, and let the patient take a tablespoonful of this solution. If this dose acts well, no repetition is necessary for the present. If this dose should not be sufficient, we prepare a new potence by throwing away three tablespoonfuls of the former solution and substituting four tablespoonfuls of fresh water, shaking the mixture well. We give a spoonful of this second solution, twenty-four hours after the first had been given, and, if necessary, a third spoonful prepared in the same way, and even a fourth and fifth, after which we await the result, without thinking either of improvement or exacerbation.