But it ought to be well known that the development of all the main parts of the body has been completed at the end of the second month. At that time, the mother rarely does more than suspect the coming of the child, and events which she believes to "mark" the child, usually occur after the fourth or fifth month, when the child is substantially formed, and it is impossible that many of the effects supposed to occur could actually occur. Indeed, it is now believed that most errors of development, such as lead to the production of great physical defects, are due to some cause within the embryo itself, and that most of them take place in the first three or four weeks, when the mother is by no means likely to influence the course of embryological development by her mental attitude toward it, for the very good reason that she knows nothing about it. Unless she is immured or isolated from the world, nearly every expectant mother sees many sights of the kind that, according to popular tradition, cause "marks." Why is it that results are so few? Why is it that women doctors and nurses, who are constantly exposed to unpleasant sights, have children that do not differ from those of other mothers? Darwin, who knew how to think scientifically, saw that this is the logical line of proof or disproof. When Sir Joseph Hooker, the botanist and geologist who was his closest friend, wrote of a supposed case of maternal impression, one of his kinswomen having insisted that a mole which appeared on her child was the effect of fright upon herself for having, before the birth of the child, blotted with sepia a copy of Turner's _Liber Studiorum_ that had been lent her with special injunctions to be careful, Darwin[27] replied: "I should be very much obliged, if at any future or leisure time you could tell me on what you ground your doubtful belief in imagination of a mother affecting her offspring. I have attended to the several statements scattered about, but do not believe in more than accidental coincidences. W. Hunter told my father, then in a lying-in hospital, that in many thousand cases he had asked the mother, before her confinement, whether anything had affected her imagination, and recorded the answers; and absolutely not one case came right, though, when the child was anything remarkable, they afterwards made the cap to fit." Any doctor who has handled many maternity cases can call to mind instances where every condition was present to perfection, for the production of maternal impression, on the time-honored lines. None occurred. Most mothers can, if they give the matter careful consideration, duplicate this experience from their own. Why is it that results are so rare?