Another set of observations, leading to precisely the same
conclusions, have been made by F. B. Chavasse of Liverpool. He terms
the potential agglutination of the fœtal corpuscles by the mother’s
serum, and of the maternal corpuscles by the serum of the fœtus, the
“maternal threat” and the “fœtal threat” respectively, and states
that there is no obvious relationship between the “fœtal threat” and
eclampsia or the toxæmias of pregnancy. The inference is therefore
justified that there is no transference of the agglutinating
substances in either direction across the placental membranes. No
chemical “immunity” is acquired, therefore, on either side, since
the protection is mechanical. This agrees with the fact observed
by Happ that the mother’s milk contains the same agglutinins as the
serum of her blood; but these do not have any deleterious effect
upon the infant, and are therefore either not absorbed at all or are
destroyed in the process of digestion.
The statement that the blood group of an infant is not necessarily
the same as that of its mother can be amplified, for it has been
found that blood groups are inherited on a definite plan, so that if
the groups of the parents be known, certain predictions can be made
as to the possible groups that may be found among their offspring.
Many characters in animals and plants have been shown during the last
twenty years to be transmitted according to the Mendelian plan of
inheritance, but up to the present time very few normal characters in
man have been isolated, and their manner of inheritance demonstrated,
though a number of pathological conditions have been shown to conform
to the theory. It is therefore of much interest to find that the
inheritance of blood groups in man can be quite satisfactorily and
consistently explained in Mendelian terms.
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