Patience and perseverance, with medical acumen, are the first requisites-but before this there must be a belief and confidence in the truth of the statements, the correctness of the theory, and the value of the method to be employed; with this there must also be an optimism on the part of the physician which begets a confidence in the patient, which will do much toward reaching the desired result. Unless much time, thought, study, and effort can be given to each case of cancer, I should deprecate any attempt to treat it medically, and rather risk at once the chances of surgery, poor as they are. It was for fear of harm following an incomplete understanding of, and an imperfect or careless carrying out of the line of practise which I had pursued satisfactorily for thirty years and more that I hesitated and delayed so long before urging it generally. But the steady rise in mortality under the ordinarily accepted treatment has impelled me to strive to make clear what I conceive to be the correct view of its nature and cause, and the approximately correct treatment of cancer. From what has preceded in these and former lectures it will be seen at once that rational and right internal treatment must proceed and continue along the lines previously indicated relating to the biochemistry of cancer. Some tissue cells have taken on wrong and rampant action, of a reproductive character, owing to an erroneous metabolism, which has induced a deranged or disordered blood current, and some measures are to be devised and carried out to restore the bodily functions to a normal state. The first line of medical treatment, therefore, after preventing the introduction of animal protein, coffee, and alcohol by dietary measures, is to seek to restore to normal the various bodily secretions and excretions. The urine, by repeated, complete, volumetrical analysis, serves as a constant guide along many lines, which I considered pretty fully in the former lectures and need not repeat now. In one private case of cancer of the breast the total amount of urine passed each day was measured and recorded daily, almost without an exception, for a whole year, and specimens of the same were carefully analyzed and studied almost every week. The total quantity of solids, which was at first only one half what the body weight called for, was brought up to about normal as the condition of the patient improved.