Coca and Cocaine : $b Their history, medical and economic uses, and medicinal preparationsMartindale, William
History
Coca and Cocaine : $b Their history, medical and economic uses, and medicinal preparations
Martindale, William
Coca; Cocaine
=Emplastrum Cocainæ.= 1 dissolved in 50 of lead plaster heated in a
water bath.
Useful for intercostal neuralgia, sciatica, tender corns, bruises, &c.
=Oleatum Cocainæ.=
A saturated solution of the alkaloid in oleic acid; heated, one part
will dissolve in two parts of oleic acid; it may be further diluted
with oleic acid or oil. Has not proved so satisfactory a preparation as
=Oleum cum Cocaina.=
A 2 per cent. solution, more or less, if ordered, in almond oil, is
mostly used. This is useful for earache. For the eye a 2 per cent.
solution in castor oil is used; for catheters, a solution in equal
parts castor and almond oils does well, it is viscid, and does not
congeal in winter.
=Suppositories= and =Pessaries of Cocaine= have ½ grain (or more, if
ordered) in each with cacao-butter.
=Tabellæ Cocainæ=, Cocaine Tablets. ¹⁄₂₀ grain in each, with chocolate
(or more, if ordered).
_Dose._—1 every quarter, half-hour, or hour, quickly eaten and
swallowed. Useful for sea-sickness, chloroform or alcohol sickness,
sickness of pregnancy, &c.
=Unguentum Cocainæ.= 1 in 30 of lard or lanoline (more or less, if
ordered). Cocaine is soluble 1 in 2 of anhydrous lanoline if gently
warmed.
Useful where absorption is required, as in facial neuralgia, shingles,
eczema, erysipelas, urticaria, and pruritus.
=Vaselinum Cocainæ.= 4 per cent. (more or less, if ordered).
Suitable for the eye; is very bland; also for smearing catheters,
burns, scalds, &c.
=Cocainæ Citras=, Citrate of Cocaine.
_Dose._—¹⁄₂₀ to 1 grain or more.
Is in deliquescent small white crystals; used by dentists.
=Cocainæ Hydrobromas=, Hydrobromate of Cocaine.
_Dose._—¹⁄₂₀ to 1 grain, in a pill or solution. Is a stable salt, in
odourless, small, white, hard, acicular crystals.
=Cocainæ Hydrochloras=, Hydrochlorate of Cocaine (_Off._).
_Off. Dose._—⅕ to 1 grain, but less and more may be given, in aqueous
solution, pill, or pastil.
This salt has been most used: if pure it is in hard, colourless, short,
acicular, granular-looking crystals, or, now more frequently met with,
in light, shining, lamellar crystals, free from odour and almost
tasteless; being soluble in half its weight of water, the tingling
numbness and local anæsthesia which it produces on the tongue are more
intense than that produced by pure cocaine.
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