Coca and Cocaine : $b Their history, medical and economic uses, and medicinal preparationsMartindale, William
History
Coca and Cocaine : $b Their history, medical and economic uses, and medicinal preparations
Martindale, William
Coca; Cocaine
One-sixth of a grain in each with gelato-glycerine basis. Useful in hay
fever, sometimes combined with ¹⁄₁₂₀ grain of Sulphate of Atropine in
each.
=Injectio Cocainæ Hydrochloratis Hypodermica.= 1 in 20.
_Dose._—2 to 10 minims. For sciatica and many local affections acts
better than morphine.
=Hypodermic Lamels= are prepared containing ¼ grain in each.
=Lamellæ Cocainæ, Discs of Cocaine= (_Off._).
Discs of gelatine, each containing ¹⁄₂₀₀ grain of hydrochlorate of
Cocaine. These should be prepared in an atmosphere carefully freed
from dust and germs of fungi and disease. Also prepared containing
¹⁄₅₀ grain in each, and in combination with Atropine, Homatropine, and
Physostigmine.
=Liquor Cocainæ Hydrochloratis= (_Off._) 10 per cent. SOLUTION OF
HYDROCHLORATE OF COCAINE.[31]
_Dose._—2 to 10 minims. Hydrochlorate of Cocaine 100, Salicylic Acid
1½, Boiling Distilled Water to produce 1,000 fluid parts when cold.
[Footnote 31: This forms a stable 10 per cent. solution, which
for the use of oculists may be diluted to a 2 per cent. solution,
and still remain free from tendency to develop fungoid growths.
The salicylic acid remains as free acid in the mixture, as with
perchloride of iron it gives a more permanent violet coloration than
the so-called salicylate of cocaine. The official solution may be used
as an application for producing local anæsthesia or for hypodermic
injection, for which purpose it is found to be unirritating. A
solution up to the strength of 50 per cent. may be prepared in
salicylic acid solution of the above strength, which is nearly
saturated.]
=Pastillus Cocainæ Hydrochloratis.= ¹⁄₂₀ grain in each (to ⅒ or ⅕
grain, or more if ordered).
Useful in allaying irritation of the throat and hoarseness. They
invigorate the vocal organs of singers and public speakers.
=Pastillus Cocainæ et Morphinæ= contains ¹⁄₃₀ grain Cocaine and ¹⁄₆₀
grain morphine. Useful for coughs.
=Pilula Cocainæ Hydrochloratis.= ⅕ grain in each (or more, if
ordered), with sugar of milk and syrup _q.s._ to make a grain pill.
=Tabloids of Hydrochlorate of Cocaine.= ⅒ and ⅙ grain each.
Are prepared for hypodermic injection.
=Trochisci Cocainæ Hydrochloratis.= ¹⁄₁₂ grain in each. Used for
similar purposes to the pastils.
=Cocainæ Salicylas.=
_Dose._—⅕ to 1 grain or more.
Is in minute snow-white crystals, slightly deliquescent, and is
recommended for the use of oculists, as it forms a solution which keeps
well.
In spasmodic asthma the hypodermic injection of a good dose (6 grains)
at the beginning, relieves the attack.—B.M.J. ii./86,117.
=Dentifricium Cocainæ.=
Phosphate of Calcium (dry), 2 ounces.
Orris, in powder, 1 ounce.
Myrrh, in powder, 30 grains.
Mix, and add in solution:—
Cocaine, 1½ ”
Oil of Eucalyptus, 12 minims.
Triturate well together and add ammoniacal solution of carmine, 15
minims. Mix well and sift.
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