We shall not follow the discussions which arose at Edinburgh about the succession to Dr. Rutherford’s chair of the Practice of Physic, nor the circumstances which led to Dr. John Gregory’s appointment. Suffice it to say that on the death of Dr. Whytt, Cullen consented to accept the chair of the Theory of Physic in 1766, and that subsequently an arrangement was made by which the two professors lectured alternately on the Theory and Practice of Physic, to the still greater advantage of the now celebrated school. This appointment was strongly promoted by both the Monros, and by an address signed by 160 medical students. The arrangement now made lasted till Dr. Gregory’s death in 1773, when Cullen became sole Professor of the Practice of Physic. Black was brought to Edinburgh to succeed Cullen in the Chair of Chemistry. Cullen’s principal works are the “Nosology,” a synopsis and classification of diseases, with definitions, which obtained wide popularity, although only an approximation to a sound system; and his “First Lines of the Practice of Physic,” 4 vols., 1778-85, which went through numerous editions. One of its especial merits was that it pointed out more clearly than preceding works the extensive and powerful influence of the nervous system on disease. It is now held as the defect of his system that it was too theoretical, and that its views were not adequately supported by facts. It cannot be denied that Cullen had but moderate anatomical and physiological knowledge, and this has prevented him from leaving works capable of being read with much profit by the practitioners of the present day. It is after all on William Cullen’s personal influence on the School of Medicine, which he did so much to maintain, that his fame will chiefly rest. The character of this influence is honourable and stainless. Dr. James Anderson has left in unequivocal language a record of his bearing in his conspicuous position which does equal honour to his intellectual energy and to his qualities of heart. Dr. Cullen, he says, was employed five or six hours a day in visiting patients and prescribing by letter; lecturing never less than two hours a day, sometimes four; yet, when encountered, he never seemed in a hurry or discomposed—always easy, cheerful, and sociably inclined. He would play at whist before supper with as keen interest as if a thousand pounds depended on it.