name of the port whence it is shipped.
[Illustration: Jalap (_Ipomaea Purga_); about half natural size.]
Jalap has been cultivated for many years in India, chiefly at
Ootacamund, and grows there as easily as a yam, often producing clusters
of tubers weighing over 9 lb.; but these, as they differ in appearance
from the commercial article, have not as yet obtained a place in the
English market. They are found, however, to be rich in resin, containing
18%. In Jamaica also the plant has been grown, at first amongst the
cinchona trees, but more recently in new ground, as it was found to
exhaust the soil.
Besides Mexican or Vera Cruz jalap, a drug called Tampico jalap has been
imported for some years in considerable quantity. It has a much more
shrivelled appearance and paler colour than ordinary jalap, and lacks
the small transverse scars present in the true drug. This kind of jalap,
the Purga de Sierra Gorda of the Mexicans, was traced by Hanbury to
_Ipomaea simulans_. It grows in Mexico along the mountain range of the
Sierra Gorda in the neighbourhood of San Luis de la Paz, from which
district it is carried down to Tampico, whence it is exported. A third
variety of jalap known as woody jalap, male jalap, or Orizaba root, or
by the Mexicans as Purgo macho, is derived from _Ipomaea orizabensis_, a
plant of Orizaba. The root occurs in fibrous pieces, which are usually
rectangular blocks of irregular shape, 2 in. or more in diameter, and
are evidently portions of a large root. It is only occasionally met with
in commerce.
The dose of jalap is from five to twenty grains, the British
Pharmacopeia directing that it must contain from 9 to 11% of the resin,
which is given in doses of two to five grains. One preparation of this
drug is in common use, the _Pulvis Jalapae Compositus_, which consists
of 5 parts of jalap, 9 of cream of tartar, and 1 of ginger. The dose is
from 20 grains to a drachm. It is best given in the maximum dose which
causes the minimum of irritation.
The chief constituents of jalap resin are two glucosides--_convolvulin_
and _jalapin_--sugar, starch and gum. Convolvulin constitutes nearly
20% of the resin. It is insoluble in ether, and is more active than
jalapin. It is not used separately in medicine. Jalapin is present in
about the same proportions. It dissolves readily in ether, and has a
soft resinous consistence. It may be given in half-grain doses. It is
the active principle of the allied drug _scammony_. According to Mayer,
the formula of convolvulin is C34H50O16, and that of jalapin C31H50O16.
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