Epitome of the Pharmacopeia of the United States and the National Formulary: With CommentsHewlett, Albion Walter
Science
Epitome of the Pharmacopeia of the United States and the National Formulary: With Comments
Hewlett, Albion Walter
Medicine -- Formulae, receipts, prescriptions; Pharmacopoeias -- United States
DOSAGE: 0.25 Gm. or 4 grains (U.S.P.)
=*Cocaina (Cocain.), Cocaine, U.S.P.=--An alkaloid obtained from coca
leaves.
Large colorless prisms or a white powder; odorless. Slightly
soluble in water (1:600) and freely soluble in alcohol (1:6.5) and
in chloroform (1:0.7).
ACTION AND USES: A local anesthetic, paralyzing the
peripheral sensory nerves and also contracting the blood
vessels. Acute systemic poisoning is often caused by its
local use on mucous membranes. Stimulant to the central
nervous system, but such use is inadvisable because of
danger of habit-formation.
DOSAGE: 0.015 Gm. or 1/4 grain (U.S.P.).
_Oleatum Cocainae (Oleat. Cocain.), Oleate of Cocaine, N.F._--Cocaine
(5%) in alcohol, oleic acid and olive oil.
=*Cocainae Hydrochloridum (Cocain. Hydrochl.), Cocaine Hydrochloride,
U.S.P.= (Cocaine Chloride, Cocainum Hydrochloricum, P.I.).
Colorless crystals, flaky leaflets or a white powder; odorless.
Freely soluble in water (1:0.4) and in alcohol (1:3.2), and soluble
in chloroform (1:12.5). Incompatible with borax, mercuric chloride,
alkalies and alkali carbonates, phenol, tannic acid, mercuric
oxide, and soluble silver salts.
ACTION AND USES: Local anesthetic.
DOSAGE: 0.015 Gm. or 1/4 grain (U.S.P.). For local anesthesia in 0.2
to 1.0 per cent. solution when used hypodermatically, and in 1 to 4
per cent. solution when applied to mucous membranes.
=Cocculus Indicus (Coccul. Ind.), Cocculus Indicus, N.F.= (Fish Berry,
Indian Berry).--A fruit.
ACTION AND USES: Source of picrotoxin. An alcoholic
extract has been used for destroying pediculi.
_Tinctura Cocculi Indici (Tr. Coccul. Ind.), Tincture of Cocculus
Indicus, N.F._--Cocculus indicus (10%) in diluted alcohol. Absolute
alcohol content about 45 per cent.
=Coccus (Coccus), Cochineal, U.S.P.=--A dried insect.
ACTION AND USES: Coloring agent.
_Liquor Cocci (Liq. Cocci), Cochineal Color, N.F._--A
glycerin-alcohol-water solution of cochineal.
=Cocillana (Cocillan.), Cocillana, N.F.=--A bark.
ACTION AND USES: Nauseant expectorant, similar to but
without advantage over ipecac. The proprietary syrup
contains heroin.
DOSAGE: 1 Gm. or 15 grains (N.F.).
_Fluidextractum Cocillanae (Fldext. Cocillan.), Fluidextract of
Cocillana, N.F._--Cocillana (100%). Absolute alcohol content about 60
per cent.
DOSAGE: 1 Cc. or 15 minims (N.F.).
=*Codeina (Codein.), Codeine, U.S.P.= (Methylmorphine).--An alkaloid
obtained from opium, or prepared from morphine by methylation.
Colorless, translucent prisms or a white powder; odorless. Slightly
soluble in water (1:120) and freely soluble in alcohol (1:2) and in
chloroform (1:0.5).
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