Thus there seemed a prospect that the young Charles would some day unite the kingdoms of Castile, Aragon, France, the Milanese, and the kingdom of Naples, with the hereditary dominions of the House of Hapsburg. Had this ever come about, the rest of Germany must have submitted, and the descendants of the poverty-stricken Frederick III. would have found themselves masters of an empire over most of the Teutonic and Latin races of the continent. But the day dream was not to last. In November 1504, Isabella died, and Ferdinand, determined to retain his hold as regent of Castile, made haste to conciliate Louis XII. At Blois, in October 1505, he agreed to marry Germaine de Foix, the niece of the French king. To her the French claims on Naples were to be resigned, which, however, were to revert to Louis XII. in default of her having issue by Ferdinand. Ferdinand further promised to Louis a sum of money, and an amnesty to the French party in Naples. In the June of the following year, 1506, Ferdinand was indeed obliged to surrender the regency of Castile to Philip and Joanna; but in September the Archduke Philip died at Burgos; the unfortunate Joanna was declared to show signs of madness,[22] and Ferdinand, by the help of Cardinal Ximenes, secured, though with difficulty, the government of Castile. Thus the quarrel between Louis XII. and Ferdinand was temporarily accommodated, and Ferdinand was secure in Spain and in Naples. Meanwhile, in France the national hostility to a foreigner had been aroused. The Estates-General at Tours (May 1506) prayed the King to abandon the intended match between Claude and Charles, and to marry her to Francis of Angoulême, the heir-presumptive to the crown, who was ‘entirely a Frenchman.’ Maximilian, irritated at the failure of his schemes, now broke with Louis. In 1507, he summoned the Diet to Constance, and passionately demanded help of the empire. ‘The King of France,’ he said, ‘wishes to rob the Germans of the Imperial crown, the highest dignity of the world and the glory of our nation.’ In return for a promise to reorganise the Imperial Chamber, he received a contingent from the Diet; he also took a body of Swiss mercenaries into his pay. Crossing the Brenner, he reached Trent in February, 1508, and there, with the consent of the papal legate, declared himself Emperor-elect. | The League of Cambray. Dec. 10, 1508.