“The dog had been prepared beforehand by the attendant. Little empty bottles were attached to the collecting tubes, and as soon as the dog saw Pawlow, he seemed to be very happy, and wagged his tail, and his eyes gave evidence of satisfaction; but there was no flow of saliva until Professor Pawlow brought near to his nose a bottle containing some powdered meat. He took out the cork in the presence of the dog, turned out a little of it in his hand, shook it in the bottle and brought it near to the dog’s nose. The dog began to sniff it, licked his chops, snapped his jaws, reached out after it, and in less than two minutes the saliva began to flow very profusely, and it was not more than fifteen or twenty seconds before the saliva was pouring down into the bottles. “Professor Pawlow, then, after holding the bottle out before the dog for about thirty seconds, put the stopper into it, and put it behind him out of sight, and in a very few seconds the saliva ceased to flow. Then he brought it back again, showed it to the dog, brought it near his nose, allowed him to smell it but kept it just out of his reach all the time, and the saliva poured out again freely. He continued this until the dog finally made up his mind he was not going to get any meat, and when the powder was brought near to him he paid no attention to it, but turned his head around and looked very disappointed and very ugly, and at that point, the saliva ceased to flow. “That was a very remarkable thing to me. The meat was right there, he could smell it, but he knew he was not going to get it, so he was angry, and as his state of mind changed, the secretion of saliva was wholly arrested. I was very much surprised. Of course, I believe thoroughly in the importance of being in a happy state of mind when eating, but I really did not appreciate thoroughly the importance of those things; I did not fully appreciate how positive an inhibitor of the activity of the salivary glands an unhappy state might be. “But a common experiment made in India shows the same idea. When an Anglo-Indian has lost anything of value, he has his whole family of servants brought to him to find out which one has stolen it. A common test is to stand them all up in a row, and then to give each one a morsel of dry rice to chew. They must chew this rice for five minutes, and then the master goes around and examines each man’s mouth. The mouth which is dry is the mouth of the culprit, and the state of that man’s mind has the effect of arresting the flow of saliva. Pawlow has shown that this is a positive physiologic law and operates upon the dogs as well as upon human beings.