From the chart and table, the number on the surface of comparison of the white blood corpuscles is seen to have more than doubled itself in the first seven months, and that this increase was solely dependent on the flooding of the blood by lymphocytes. The nucleated or bone-marrow elements and the large mononuclear cells remained continuously at the same level during the whole period. The changes in the percentage proportions ran somewhat differently. The percentages rose from 35 to 66% for the lymphocytes only, whilst for the other forms they distinctly fell: for the nucleated from 44% to 22% and for the large mononuclear from 18% to 9%. It was only in the course of the second year that a very considerable relative and absolute increase of the eosinophil cells appeared: the values rose gradually from about 1.0% to 28.9% or from 0.5 to 13.9 on each comparison area. The last examination of the blood in this animal was made on April 30, 1890, that is, two years after the removal of the spleen. The animal was quite healthy, bore four healthy young guinea-pigs by a father whose spleen had been removed. The young have a completely normal spleen, and their blood likewise shows no abnormalities. [Illustration: CHART TO EXPT. No. I. (cp. Table, page 89. The figures in the chart refer to comparative surfaces.) Thick line--total number of leucocytes Broken line--lymphocytes Thin line--number of nucleated, pseudo-eosinophil cells Double line--large mononuclear cells Dotted line--eosinophil cells] TABLE I. Key to columns: A - Leucocytes B - Pseudo-eosinophil cells C - Lymphocytes D - Large mononuclear cells E - Eosinophil cells F - Nigrosinopil cells G - On comparative surfaces