Jaundice: Its Pathology and Treatment: With the Application of Physiological Chemistry to the Detection and Treatment of Diseases of the Liver and PancreasHarley, George
Science
Jaundice: Its Pathology and Treatment: With the Application of Physiological Chemistry to the Detection and Treatment of Diseases of the Liver and Pancreas
Harley, George
Jaundice
Soda . . . . . |
Potash . . . . | Inorganic salts . 16·56
Iron . . . . . |
Whereas a specimen of normal bile taken from the gall-bladder of a
woman aged sixty-one, was of a specific gravity of 1020, and contained
in 1000 parts:--
Water . . . . 933·27
Solids . . . 66·73
------
1000·00
=======
{84}
Pigment . . . . |
Bile acids . . | Organic matter . 56·73
Cholesterine . |
Sugar . . . . . |
Soda . . . . . |
Potash . . . . | Inorganic salts . 10·00
Iron . . . . . |
The difference in composition of these two biles is very striking. The
one contains more than four times as much solid matter as the other;
and if the relative amount of organic, and inorganic substances be
compared, the curious fact is observed, that the difference in the
amount of solids in the two cases, is almost entirely due to the change
in quantity of organic matter. The inorganic salts have not even so
much as doubled themselves in the abnormal bile. Whence is this? Soda
is the chief inorganic substance found in bile, and we have seen that
it occurs in the form of glycocholate, and taurocholate of soda,
substances which, as before remarked, are re-absorbed from the
distended ducts, and gall-bladder into the circulation, from whence
they are constantly being eliminated with the urine; and this, no
doubt, is one of the causes why the inorganic salts are proportionally
in such small quantity in the abnormal bile of jaundice from
obstruction.
{85} Fifthly,--In the abdomen was a considerable quantity of dark
straw-coloured serum, which on the addition of strong sulphuric acid
became of a fine emerald-green colour, in consequence of the presence
of bile. Traces of sugar were also present in the effused liquid. The
serum had only collected in the latter weeks of the patient's life, and
after the shrinking of the liver was observed to have begun.
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