Several physicians in the West Indies have tried it, and amongst them Dr. Maldur, who treated four lepers in Santa-Caza da Misericordia, with, he believed, great benefit; other trials, however, failed, and the remedy has been laid aside. The foregoing reports of the results of the treatment of leprosy with different specific remedies, are taken from the experience of the late Dr. Danielssen, who spent half a century trying to cure leprosy, and we shall now give some of the various methods of treatment he used. Early in the development of bacteriological research, Dr. Danielssen already suspected the bacterial nature of the disease, and began to use germicides. _Carbolic acid_ was given in solution, 8 grains to 8 ounces, 1 tablespoonful four times daily, and he went so far as to give 20 grains to 8 ounces in the same way. Externally, he applied carbolic acid as an ointment or a lotion. It was used by fifty-three lepers from three to eighteen months, but had no effect on the disease. _Creasote_ was used in 1838 by the late Dr. Hjort, and later by Danielssen, without any good effect. Prof. Langerhans of Madeira, told Dr. Danielssen that he had seen several lepers on Teneriffe, whom Dr. Perez, at his suggestion, treated with creasote in increasing doses, with good effect, and he therefore asked Dr. Danielssen to try it once more. Consequently, creasote in pills (0.025 gr. in each pill) was administered to five tuberous lepers, in an early stage of the disease. They took the pills for six months without any effect on their leprosy. Two of them took the pills for fifteen months, and as many as 20 pills a day. The pills did neither good nor harm; their influence on leprosy was _nil_. In the early years of the Lungegaard’s hospital (1849-50) glacial phosphoric acid was largely used without benefit. _Phosphorus_ was given in doses of 2 to 3 milligrammes daily. After some months it was given up because it caused indisposition and destroyed the appetite, while the leprosy remained unaltered. _Arsenic_ has been used by many physicians in the treatment of leprosy. Dr. Danielssen tried it in the form of Fowler’s solution, and the so-called Asiatic pills, in gradually increasing doses, but the prolonged use of arsenic, instead of doing good, made the patients worse, causing gastro-enteritis and emaciation. The emaciation caused diminution in the size of the tubers, which has been regarded by many physicians as an improvement; but this is a fallacy, for, when the patient regains his former good condition, the nodules regain their former size. _Ichthyol_ was tried internally in the form of pills, 10 centigrammes thrice daily, increased up to 2 grammes daily; but no benefit was observed, although it was continued for almost a year.