IT appears, by what hath been already said, that a Loathing at Stomach was a certain Sign of Infection; and upon a Continuance of it, it was necessary that there should ensue a Defect of Nourishment and Strength, which made a Person much more liable to the worst Influences of the Distemper, and even to Erosion and Sphacelation of the Stomach. _DEAFNESS joined with Drowsiness, were Signs the_ Parotides _would soon appear_. _WHEN Buboes went in again without due Evacuation, and while bad Symptoms continued, Matters were generally doubtful, and for the most Part very dangerous._ I always looked upon my Labours to be defeated, whensoever these Tumours disappeared of a sudden without any manifest Cause; for it was owing to the Retreat of the Venom inwards, where it made terrible Mischief, and was extreamly difficult to be got again to the Surface; yet if Sweats broke out, that the Patient could well bear, it was not uncommon for them to return, and bring again Matters into an hopeful State. _WHENSOEVER these Tumours are discoloured, especially tending to Blackness, or do not suppurate, or are insensible, it may be pronounced the Patient will be worse._ _THE more Buboes there are, so that they suppurate, the better._ _CARBUNCLES are always more dangerous than Buboes._ BOTH on Account of their sharper Pain, and greater Difficulty to cure. _THE smaller the Carbuncles are in Compass, and their Situation remote from the_ Viscera, _greater Vessels, Tendons, and Nerves, and the fewer they are in Number, by so much it is the better; and, on the contrary, when they spread like a Gangrene, and are near the principal Parts, as the Breast or Belly, and also are numerous, or livid, the Fate of the Patient may be pronounced desperate._ _THE pestilential_ Tokens, _especially when they are deep, are the sure and speedy Messengers of Death_. FOR a general Mortification commonly follows these particular ones: although there is sometimes (as before observed) some Time given between one and the other, as for two or three Days. _A Complication of bad Symptoms, together, precipitates the Patient into another World._ NAY, sometimes when there are many Symptoms of Recovery, the obstinate Continuance of one bad is enough to determine the Patient’s Fate. _FROM the inconstant Appearance of the Urine, there can be no certain Judgment made._ THE Urine indeed of these Patients is generally not to be distinguished from that of healthful Persons, although sometimes its Stench is not to be endured; this a certain Physician found to his Cost, who taking the Urinal too near, was infected by the Scent, fell ill, and in three Days died. _THE Pulse, which in all other Diseases is almost a certain Index, in this Sickness could not be at all trusted to._ _THOSE who were comatous in the Beginning or Height of the Disease, seldom escaped._