With our magnificent hospitals, second to none in the world, our large medical colleges and dispensaries, and the establishment of so large and excellent an institution as the Civiale Agency, the main offices being now transferred from Paris to this city, New York may justly claim to be the great medical centre of the United States, and sooner or later of the world. We maintain now, as we have always maintained, that the surest and best way to drive quacks and humbugs from any branch of medicine, is to have some of our very ablest and most honorable physicians make such a branch their specialty, and such is the course now being pursued by the Civiale Agency. The very fact that it takes its name from and is engaged in manufacturing and prescribing the remedies of France's most illustrious specialist, Prof. Jean Civiale, is by itself evidence enough of its medical value and professional integrity. Our feelings upon these matters, _i.e._, the great importance of their bearing upon both individual and national vigor and prosperity, the necessity for driving from this field of practice those quacks and humbugs who entrap the foolish and ignorant, those cheap and worthless remedies that flood the drug market--our feelings upon these matters are, we repeat, very strong; and hence, when we find an institution for the treatment of these diseases conducted upon the highest moral, medical and business principles by men of undoubted medical and business standing and integrity, we feel that we cannot endorse them too heartily. The _Tribune and Farmer_, of New York city, in its current issue of July 26th, 1884, says "AN EXCEPTION TO THE RULE." "The propriety of devoting editorial space to the subject-matter of any medical advertisement that may appear in our columns may be doubted by some, and indeed, were it not for our personal knowledge of the skill and integrity of the Medical Director of the Civiale Remedial Agency of New York (whose advertisements will be found elsewhere in this issue), we should deem ourselves more than guilty were we to utter a word of endorsement as to the efficacy of their system of treating that serious class of diseases in men which has been generically termed Nervous Debility, and which for so many years has been, and is at present, made the stalking-horse for impudent swindlers, quacks and impostors to palm off worthless and often injurious compounds on their suffering fellow-men. "Let it be understood, then, that we know whereof we speak, and that our object is simply to furnish those who are afflicted with such reliable information as will enable them to determine the true character of their disease, and the best means to be adopted for a cure.