The fourth of these great surgeons at the North of Italy was William of Salicet. He was a pupil of Bruno of Longoburgo. Some idea of his practice as a surgeon may be obtained from even the first chapter of his first book. He begins with the treatment of hydrocephalus--or, as he calls it, "water collected in the heads of children newly born." He rejects opening of the head by incision because of the danger of it. He had successfully treated some of these difficult cases, however, by puncturing the scalp and membrane by a cautery, a very small opening being made and fluid being allowed to escape only drop by drop. William did not quote his predecessors much, but depended to a great extent on his own experience. He has many interesting details of technique with regard to the special subject of surgery of the nose, the ear, the mouth; and he did not even hesitate to treat goitre when it grows large, and says that if the sac is allowed to remain it should be thoroughly rubbed over on the inside with "green ointment." He warned "that in this affection many large bloodvessels make their appearance, and they find their way everywhere through the fleshy mass." A very interesting development of surgery along a line where it would probably be least expected was in plastic surgery. In the first half of the fifteenth century the two Brancas, father and son, performed a series of successful operations for the restoration of the nose particularly, and the son invented a series of similar procedures for the restoration of mutilated lips and ears. The father seems to have built up the nose from other portions of the face, possibly using, as Gurlt suggests, the skin of the forehead, as the Indian surgeons had done, though without any known hint of their work. Fazio, the historian of King Alphonso I. of Naples, who died in 1457, describes the favourite operation of Antonio Branca, the son, who in order not to disfigure any further the face in these cases, made the new nose from the skin of the upper arm; and in anticipation of Tagliacozzi, who attracted much attention by a similar operation in the latter half of the sixteenth century, separated the new nose from the arm sometime during the third week. There is abundance of other evidence as to the Brancas' work from contemporary writers--for instance, Bishop Peter Ranzano the annalist, the poet Calenzio, and Alexander Benedetti, the physician and anatomist--so that there can be no doubt of the fact that this wonderful invention in surgical technique was actually made before the close of the Middle Ages.