On the 16th of April, 1817, Mr. Adams received letters from President Monroe, with the information that, with the sanction of the Senate, the Department of State had been committed to him; a trust which he accepted with a deep sense of its weight and responsibility. In compliance with Mr. Monroe's request, he made immediate arrangements to return to the United States. On presenting his letters of recall to Lord Castlereagh, congratulations on his appointment were attended with regrets at his removal from his mission. Mr. Adams stated that the uncertainty of his acceptance of the office of Secretary of State had prevented an immediate appointment of his successor, but that he was instructed in the strongest manner to declare the earnest desire of President Monroe to cultivate the most friendly intercourse with Great Britain. He gave the same explanation to the Prince Regent, at a private audience, who replied by an assurance of his disposition to continue to promote the harmony between the two nations which was required by the interests of both. There was no formality in the discourse on either side, and the generalities of mutual assurance were much alike, and estimated at their real value. In reply to the inquiries of the Prince, the names of the members of Mr. Monroe's cabinet were mentioned. He was not acquainted with any of them, but spoke in handsome terms of Mr. Thomas Pinckney and Mr. Rufus King, and asked many questions concerning the organization of the American government. Lord Castlereagh, in his final interview with Mr. Adams, made numerous inquiries relative to the foreign relations of the United States, especially in regard to Spain, and again expressed the desire of the British government not only to remain at peace themselves, but also to promote tranquillity among other nations. Prince Esterhazy, in a parting visit to Mr. Adams, also assured him that the cabinets of Europe were never so universally and sincerely pacific as at that time; that they all had finances to redeem, ravages to repair, and wanted a period of long repose. After taking leave of his numerous friends in office and in private life, Mr. Adams bade farewell to London, and embarked with his family from Cowes, in the packet-ship Washington, on the 17th of June, 1817, for the United States. CHAPTER V. FIRST TERM OF MR. MONROE'S ADMINISTRATION.--STATE OF PARTIES.--SEMINOLE WAR.--TAKING OF PENSACOLA.--NEGOTIATION WITH SPAIN.--PURCHASE OF THE FLORIDAS.--COLONIZATION SOCIETY.--THE ADMISSION OF MISSOURI INTO THE UNION.