_Post-mortem Appearances._—Although the body may be relaxed at the time
of death it usually quickly stiffens—frequently in the course of ten or
fifteen minutes. The rigor mortis is persistent for some time: in the
case of Cook, poisoned by Palmer, the rigidity of the body and limbs was
said not to have passed off after two months’ interment. This is not
however invariable, as a body may be flaccid or stiff after death from
this cause as from any other. The hands are often clenched, and the
soles of the feet arched and inverted. The membranes of the brain and of
the upper part of the spinal cord are congested; and there is often
considerable serous effusions under the spinal arachnoid. The lungs are
generally loaded with dark fluid blood. The heart is usually contracted,
but sometimes the right cavities are distended like the pulmonary
vessels. The blood has been found black and liquid.
_Treatment._—Emetics are to be given at once, and repeated until very
free vomiting is induced. If the tetanic spasms have not commenced, the
stomach-pump ought to be used. Chloroform is to be given to relieve
spasm and pain, but the patient should be disturbed as little as
possible, as the least thing induces the tetanic attack. There is no
very suitable antidote, but tannic acid, in the form of green or black
tea, &c., might be given.
Iodine forms a crystallizable compound with strychnia. Dr. Bennett, of
Sydney, has recorded an instance in which he attributed recovery to the
employment of tincture of iodine. Hence from thirty minims to a drachm
of this tincture combined with the iodide of potassium may be exhibited.
In its absence, three or four ounces of animal charcoal, diffused
through water, ought to be given.
To prevent the spasms by paralyzing the motor nerves, a solution of
curare has been recommended by Dr. George Harley to be injected under
the skin; or, if it could be obtained, the active principle of this
substance, curarina, would perhaps be deserving of trial.
The patient is to be kept warm and quiet.
To separate strychnia from organic admixture the process modified from
Stas, given in the beginning of this book, is the most useful.
_Tests._—Strychnia is a white crystalline solid, very insoluble in
water, soluble in alcohol or chloroform or weak acids, and having an
intensely bitter taste.
1. Pure strychnia is not changed in color when treated with iodic acid
or with either of the strong mineral acids; but as this alkaloid
generally contains brucia, nitric acid reddens it.
2. Dissolved in sulphuric acid no change ensues; but on adding a
fragment of bichromate of potass to the solution a series of blue,
violet, purple and red tints are produced. The same result is brought
about by using ferricyanide of potassium, permanganate of potassium, the
peroxide of lead, or the black oxide of manganese.
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