As I am now over sixty years old, it seemed high time to cast about for something possessing the virtue specified, viz., making "a 'new' man out of an old one"--and to my knowledge, as I have never had five days' illness confining me to bed, or even to my room, during the said sixty years, I considered myself an easy subject for the contemplated rejuvenation; besides all this, I am what some would call a homoeopathic "crank;" and believed, and yet believe, if there be anything that can effect such a transformation it is to be found only within the lines of Homoeopathy, I immediately ordered quantum suf. of the article in question from the celebrated firm of Boericke & Tafel, and started out on the trip to the "Fountain of Youth" in full confidence that _something_ would come of it. The first day I took two doses mother tincture 10-15 drops each; no special effect noticed--no youthfulness either! Second day, ditto; third day, one dose in morning; after bank hours went to friend's sanctum and engaged in a game of chess, and while so engaged felt a growing sense of nausea and thick-headedness--so much so, that I was obliged to excuse myself and hurry to my own quarters. _Berberis_, however, did not once occur to me--I had scarce reached my room when the sense of nausea (seven minutes' lively walk, since it became really oppressive) had _full sway_, and having eaten nothing whatever since the previous evening (as I do not eat unless I am hungry) the straining was rather severe, but exactly similar to some previous attacks of "biliousness"--in feeling, and color and taste of discharges--and still _Berberis_ did not occur to me; as soon as the strain was over I was seized with a remarkable and peculiar headache; a thing of which I have no recollection whatever to have previously experienced in any shape--the sensation was that of a strong, well-defined, compressive band of iron (or some unyielding substance), about two inches wide, passing _entirely round the head, just above the ears_--it kept on growing tighter and tighter; I jumped from the reclined position on a couch, wet a folded towel in cold water, and passed it round my head so as to cover the "band;" but it gave little relief; about 10 o'clock I began to think over what I might have eaten to disagree with me so, and at last _Berberis_ came plump into sight; I at once prepared a cup of strong, strong coffee (Hahnemann's antidote, and for which I had to send to a neighbor), believing it would antidote the _Berberis_ (or rather hoping it might), and about 12 o'clock there was a slight diminution of pressure; then more coffee, black and strong, two or three mouthfuls, and again laid down; by morning the serious phase of the headache had disappeared, but I was exceedingly tremulous in nerves and unsteady in gait up to noon, when I ventured on some oatmeal and syrup--habitually, I do not eat meat, or drink tea or coffee, nor spirituous liquors, nor