“On the 13th of September last, she for the first time seemed delirious when going to bed. This was mentioned next morning to Surgeon ——, who declared it to be nervous irritability of the spine.... On the 27th, Dr. —— was called in, and at once gave his opinion that there was ailment of the womb. He then ordered small blisters on the lower part of the stomach, which in less than ten hours relieved her, and removed the mania. She had not any reason for _many_ days previous, and was sinking.... On the 3rd of October, Dr. —— fixed an instrument to support the womb; and, except during the time when the intensity of pain caused it, there was no delirium; for a few days she got claret, which seemed to excite her greatly, so it was discontinued; but on the 13th of October I was desired to give her port wine in abundance. She was excessively weak, and mania so dreadful, that she made several attempts to injure herself and me. She got as many as eight large glasses of best port on some days; strong beef-tea, chicken soup, and all the nourishment possible. It was not only suggested, but it was advised to remove her to a lunatic asylum; however, feeling that certainly nine-tenths of her time she was perfectly sane, and could know well where she was and with whom, I did not like the idea of placing so young a creature in an asylum. I kept her here, and watched her day and night; she never was left alone for one moment for three months.... I ought to mention that the order for abundance of wine, &c., was from the opinion that ‘want of blood to the brain’ caused the mania; and that the intense inflammation of all internal organs was relieved by blisters on the lower part of the stomach and by mercury.” Feb. 8. Lint removed from rectum, and wounds dressed. Is calm and rational; passed a quiet day. Feb. 10. Very restless; obliged to restrain hands and legs. Feb. 11. Better; says her head feels heavy; countenance cheerful; manner quiet and rational. Feb. 12. Very excited and irritable; constantly managing to free her hands; will allow no one near her.—2 p.m.: Is quite maniacal; has managed to irritate the wounds, and also the mammæ. To have one grain of opium in pill, and ten grains of bromide of ammonium three times a day. Feb. 13, 6 a.m. Hands again free; repeat opium. Slept afterwards till 4 p.m., when she awoke calm and rational.—9 p.m. Slept again. Feb. 14. Very restless, and at times violent. Bandages removed and jacket substituted. Feb. 15. Much better; rational, and conversing cheerfully. Feb. 16. Improving. Feb. 17. At her urgent request, hands were freed, but shortly after she became excited. Feb. 19. More sensible; had to-day symptoms of a severe bilious attack, which upset her for some days. Feb. 24. Much better; allowed to see her sister—the first time since the operation.