A loop similarly immersed in m/6 CaCl_{2} solution at body temperature remains in the great majority of cases quite motionless from the first. In some instances slight movements appear immediately after it is placed in the solution, but these soon disappear. After 25-40 minutes it is not uncommon to see the loop slowly straighten out, and at the end of this time the length of the loop is much less than it was at first. This seems to be due to a slow contraction of the longitudinal muscle layer, so slow that no movement can be observed. A difference is seen also in the shape of the loops placed in LiCl and in CaCl_{2}. The former after it comes to rest is practically its original length and is coiled up in a circle; the latter is about half its original length and is almost straight. A loop similar to the above placed in 50 c.c. m/6 LiCl + 5 c.c. m/6 CaCl_{2} behaves in a manner entirely different from loops from the same animal placed in either LiCl or CaCl_{2} alone. On being first immersed in the mixture it exhibits practically no movements. Even in cases where the control loop is active at first the corresponding loop in the mixture of LiCl and CaCl_{2} shows no movements. It remains perfectly quiet for 10-15 minutes. Then sharp constrictions appear here and there in the loop. These are followed a second or two later by violent contractions which cause the loop to coil upon itself in a most active manner. These contractions somewhat resemble those caused by BaCl_{2} in the intact intestine. They follow one another rapidly so that the loop is turned and twisted tightly upon itself. This extreme activity persists for 30-45 minutes, sometimes for an hour, while during all this time the control loops in LiCl and in CaCl_{2} are entirely motionless. These movements are not at all of the same character as those which may appear at the beginning in pure LiCl solution, and could not be considered as these same movements delayed. Such an experiment is outlined in the following table:-- Time. Loops 50 c.c. m/6 LiCl 50 c.c. placed in 50 c.c. m/6 LiCl + 5 c.c. m/6 m/6 CaCl_{2} solutions at CaCl_{2} 10:05 no movements no movements no movements 10:10 no movements no movements no movements 10:15 no movements no movements no movements 10:19 no movements violent movements begin no movements 10:25 no movements very active movements no movements 10:30 no movements very active movements no movements 10:45 no movements very active movements no movements 10:50 no movements movement less active no movements 11:00 no movements movement very slight no movements 11:15 no movements movement almost stopped no movements 11:20 no movements no movements no movements