On the whole, there is a far-reaching independence between the apparent mental variations and the seriousness of the brain affection. Light hysteric states may produce a strong absenting of the mind while severe epileptic conditions of the brain may be accompanied by very slight mental changes. Every neurasthenic state may play havoc with mental life, while grave brain destructions may only shade slightly the character or the intellect. To deal with the mental changes as if they belonged to a sphere by itself, to the soul which is well or ill through its own independent alterations without steadily relating the changes to the total organism, leads therefore necessarily to failure. The mind reflects only symptoms of the disease; the disease itself belongs always to the organism. Psychotherapy has suffered too much from the belief that the removal of mental symptoms is a cure of disease. Certainly the psychophysical symptoms may often stand in the foreground of the disease, and in that case it may be left to the special needs whether we deal with them as psychical or as physical changes. Even the patient may be made to see them in one or the other way in accordance with his special needs. To tell him that his brain cells are in disorder and that they can be cured will be the right thing for him who takes only the introspective view of his suffering and is in despair because his own will seems powerless to overcome those mental changes. For the next patient, the opposite may be wiser. The belief that his brain is ill may have induced him to give up effort of the will instead of helping along by steady self-suggestion. He will be helped more if he understands that his mind is working wrongly. But the full truth is that both mind and body are in disorder; the function of the disturbed brain cells accompanies the ineffective will, and to reenforce the will means to bring into equilibrium again the disturbed brain cells. For the psychotherapist the temptation of giving the attention to the mental symptoms only is strong. The more firmly the physician sticks to the standpoint of psychophysiology, the better he will see ailment and cure in their right proportion.