“All that could be inferred was, that though the perception of it was a positive proof of its presence, the non-perception was no proof of its not being present. As to the deceased having died from water having been poured down her throat, it was quite idle to attribute it to that. At that moment she was not living: death had already done its work. With regard to the quantity of prussic acid requisite to kill a human being, it had been proved that less than a grain would kill in some cases, as appeared by the melancholy cases so frequently referred to of the seven epileptic patients in Paris; and Mr. Cooper had proved that more than a grain existed in the stomach of the deceased. It was said that the experiments were not satisfactorily conducted—that was a question for the jury. “In considering the conduct of the prisoner, the jury must couple it with all the other evidence, in order to judge how far it bore out or contradicted the inferences that might be derived from it. It appeared that on the day in question the prisoner had gone to the Paddington station of the Great Western Railway and taken his place for Slough. He had left his great coat at the Jerusalem coffee-house, and told the waiter that he was going to dine at the West End of town. That was untrue, and he must have made that false statement for some object or other. He went down to Slough at five o’clock, and between six and seven Mrs. Ashley went round to the deceased’s house, in consequence of the noise she heard of stifled screaming. She met the prisoner in the garden in a state of agitation—so great that he could not undo the latch of the gate. She opened it for him. As to the observation she made about fearing that her neighbour was ill, she could not say that the prisoner heard it, and therefore it went for nothing. Let that pass. However, after she got in at the door of the deceased’s house, she turned round and saw the prisoner looking at her, and such was the effect upon her that she felt alarmed, and closed and fastened the door. At seven o’clock the prisoner was seen by a postboy, and he was then making towards the station. At ten minutes after seven he was at the station. He was next seen getting into the Eton omnibus, and asking to be set down at Herschel House. What his intention was in going to Herschel House does not appear. He was traced back again to the station, and an alarm having been given, a signal was made by the electric telegraph, and he was seen to alight from the railway carriage at Paddington, and was then traced home. When he was taken up next morning, and told what he was taken for, his answer was, that he knew no one at Slough. It had been suggested by his counsel that this was strictly true, as the deceased did not live exactly at Slough, but a little distance from it. It had also been suggested that he wished to prevent his wife hearing of his improper connection. It would be