The diseases of these localities are well marked. Scrofula more or less completely blights all that are born: often extinguishing life prematurely; in childhood, by hydrocephalus; in youth, by pulmonary and renal affections, which you read of as consumption and dropsy; often scarring and maiming where it does not kill, and rendering life miserable by blindness, decrepitude, or deformity; often prolonging itself as a hereditary curse in the misbegotten offspring of those who, under such unnatural conditions, attain to maturity and procreation. Typhus prevails there too, not as an occasional visitor, but as an habitual pestilence. It is impossible for me, by numbers, to give you an exact knowledge of the fatality of such spots; because, in the greater part of the City, hospitals, dispensaries, and private practice, divide with the parochial officers the treatment of the sick, and diminish the returns of sickness which those officers would otherwise have to show. But this I may tell you, as an illustration of what I mean;--that in the few houses of Seven-Step-alley and its two offsets, (Amelia-place and Turner-square,) there occurred last year 163 parochial cases of fever; in Prince’s-place and Prince’s-square, 176 cases--think, Gentlemen, if this had occurred in Southampton-place and Russell-square! that behind the east side of Bishopsgate, in the very small distance from Widegate-street to New-street, there were 126 cases; that behind the west side, from Primrose-street to Half-moon-street, there were 245 cases; that the parish of Cripplegate had 354 cases over and above the number (probably a very large one) treated by private practitioners, by hospitals, and especially by dispensaries. Similarly, though with less perfect information, I am enabled to trace fever to a terrible extent in very many other localities of the City, even on the verge of its better residences, and close behind its wealthiest thoroughfares; in Plumtree-court, in Plough-court and place, in Poppin’s-court, Neville’s-court, Blackhorse-alley, Union-court, Plough-court in Holborn, Field-lane; in the courts right and left of King-street, Smithfield, in Hanging-sword-alley and its vicinity, in Peahen-court, in Bell-alley and its neighbourhood, in Priest’s-alley, in Beer-lane, in Friar’s-alley, in Bromley’s-buildings, and in the whole large space which stretches from Ludgate-hill to beside the river. And in most of these localities, in addition to other sanitary errors, there predominates that particular one to which I am now inviting your attention--the absence, namely, of sufficient ventilation.