We shall here concern ourselves principally with the appearance or the increase of the sugar, so far as its presence according to the views hitherto held is normal. We are acquainted with a so-called alimentary glycosuria, which is occasioned by this, that the individual in question, after having eaten an excessive quantity of sugar, easily recognizes an increase of the quantity of sugar in the urine. But there are also individuals, who, though they may have eaten a very large quantity of sugar, cannot afterwards discover a trace of it in the urine. In these cases complete combustion has taken place. But here we must also next direct our attention to the fact that there are persons who, in the digestion of their food under all circumstances, excrete sugar, though perhaps in very small quantities. Others, after eating proportionately much larger quantities, excrete no perceptible sugar in the urine. Hoppe-Seyler, after having eaten 225 grammes of sugar, could find no trace of it in his urine. (Moritz.) Frerichs admits exceptions, and relates that in the case of two men he could always discover sugar in the urine after they had eaten sugar, although he considered both healthy. Then we find specialists like Budge, C. Schmidt, Mosler, Schiff, Vogel, C. Ludwig, Voit, etc., who admit, after their experiments with men and beasts, an artificial glycosuria, which is normal. Seegen, after feeding dogs with cane sugar, found inverted sugar (_invertzucker_) in the urine. The sugar which he was able to identify was of two kinds, one of them turning the polarization plane to the right, and the other turning it to the left. Experiments with champagnes, various other wines and sweetmeats, which contain great quantities of sugar, gave as a regular result perceptible sugar in the urine of many individuals. As a consequence of greater quantities being taken, an excessive glycosuria set in. Its duration depended upon the occasioning causes alone. On their removal, the quantity of sugar either returned to a minimum or entirely disappeared. * * * * *