The Messrs. Denison employ 175 hands at Mechanic Falls. Their pay roll amounts to about $5,000 per month. The mills produce 350,000 pounds of paper per month and they ship several car-loads of prepared wood-pulp, in excess of that required for their own use, weekly. The annual value of their product is not far from $300,000. They use, for sundries, each month, 300 tons of coal, 100 casks of common lime, 250 gallons of burning-oil, 28,000 pounds of chlorate of lime, 3,700 pounds of soda ash. 10,000 pounds of resin. 24,000 pounds of sal soda, 22,000 pounds of oil of vitriol, 22,000 pounds of China clay, etc. * * * * * WHEAT-MEAL BREAD AS A MEANS OF DIMINISHING TUBERCULAR DISEASE. By M. YATES, Hon. Sec. Bread Reform League, London. It is well recognized that defective mineral nutrition is an important factor in the production of rickets and bad teeth, but as its influence in predisposing toward tuberculous disease is not so clearly ascertained, will you kindly allow public attention to be directed to a statement which was discussed at the Social Science and Sanitary Congresses and which, if confirmed by further scientific research, indicates a simple means of diminishing consumption, which, as Dr. William Fair, F.R.S., says, "is the greatest, the most constant, and the most dreadful of all the diseases that affect mankind." In "Phosphates in Nutrition," by Mr. M.F. Anderson, it is stated that although the external appearances and general condition of a body when death has occurred from starvation are very similar to those presented in tuberculous disease, in starvation, "from wasting of the tissues, caused by the combustion of their organic matter, there would be an apparent _increase_ in the percentage proportion of mineral matter; on the other hand, in tubercular disease, there would be a material _decrease_ in the mineral matter as compared with the general wasting." Analyses, made by Mr. Anderson, of the vascular tissues of patients who have died of consumption, scrofula, and allied diseases, show "a very marked deficiency in the quantity of inorganic matter entering into their composition; this deficiency is not confined to the organs or tissues which are apparently the seat of the disease, but in a greater or lesser degree pervades the whole capillary system." The observations of Dr. Marcet, F.R.S., show that in phthisis there is a considerable reduction of the normal amount of phosphoric acid in the pulmonary tissues; and it is very probable that there is a general drain of phosphoric acid from the system.