The average weight of the tablets was 11·2 grains; among 12 weighed separately the weights varied from 10·5 to 12·5 grains. Analysis showed the presence of potassium iodide, guaiacum resin, extract of liquorice, powdered liquorice, starch, mineral matter—apparently a mixture of talc and kaolin—a resinoid substance, and a trace of alkaloid. The alkaloid amounted to 0·016 per cent.; it did not agree in properties with any of the common alkaloids, but agreed, so far as it was practicable to examine it, with the alkaloid of phytolacca (the American weed, poke-root, or pokeberry); the resinoid also agreed in its properties with the resinoid phytolaccin, but there are no distinctive tests by which its identity could be certainly established. The quantities of the various ingredients were estimated as accurately as possible, and the following formula was indicated: Potassium iodide 1·8 grains. Guaiacum resin 0·8 grain. Extract of liquorice 1·0 ” Resinoid (phytolaccin?) 0·9 ” Powdered liquorice 1·7 grains. Rice starch 2·0 ” Talc and kaolin 2·1 ” In one tablet. In the formula the most expensive ingredient is the phytolaccin, which is also the least certain, both as to identity and quantity. Taking the formula here given, the estimated cost of the ingredients for 50 tablets is 8d. _Gloria Pills_, price 1s. 1½d. per box, containing 40 pills, in addition to being supplied as part of the “treatment” for rheumatism, were recommended as a general laxative. It was stated in the circular enclosed with them that “Gloria Laxative Pills will cure Constipation, Torpid Liver, Piles, Headache, Dizziness, Sour Eructation, Heartburn, Bloating, Flatulence, Nausea, Sleeplessness, Mental Depression, Palpitation of the Heart, Nervousness, Kidney Trouble, and all other conditions resulting from Dyspepsia and Indigestion.” The pills were coated with talc, coloured to a chocolate colour with oxide of iron. After removal of the coating, the average weight was 1·1 grains. Analysis showed the constituents to be chiefly extracts and resins. The two samples of pills examined—namely, the gratis sample of eight pills first supplied, and the full box afterwards obtained—differed materially in composition; the former contained about 25 per cent. of powdered liquorice, 6 or 8 per cent. of powdered rhubarb, and 6 or 8 per cent. of wheat flour, while the latter contained neither liquorice nor rhubarb, and proportionately more of the soluble constituents, which appeared to consist in both cases of extracts of aloes and cascara sagrada with jalap resin. The various constituents were estimated quantitatively, but in such a mixture exact results are of course unattainable, and even the qualitative results must be given with a certain reservation. The formula indicated for the pills in the 1s. 1½d. box was: