"Twilight came on," he said, in subsequently relating the event. "The hour had long passed when it was usual for patients to call. I had just resolved to inhale the ether again and have a tooth extracted under its influence, when a feeble ring was heard at the door. Making a motion to one of my assistants who started to answer the bell, I hastened myself to the door, where I found a man with his face bound up, who seemed to be suffering extremely. 'Doctor,' said he, 'I have a dreadful tooth, but it is so sore I cannot summon courage to have it pulled; can't you mesmerise me?' I need not say that my heart bounded at this question, and that I found it difficult to control my feelings, but putting a great constraint upon myself I expressed my sympathy, and invited him to walk into the office. I examined the tooth, and in the most encouraging manner told the poor sufferer that I had something better than mesmerism, by means of which I could take out his tooth, without giving him pain. He gladly consented, and saturating my handkerchief with ether I gave it to him to inhale. He became unconscious almost immediately. It was dark. Dr. Haydon held the lamp. My assistants were trembling with excitement, apprehending the usual prolonged scream from the patient, while I extracted the firmly-rooted bicuspid tooth. I was so much agitated that I came near throwing the instrument out of the window. But now came a terrible reaction. The wrenching of the tooth had failed to rouse him in the slightest degree; he remained still and motionless as if already in the embrace of death. The terrible thought flashed through my mind that he might be dead--that in my zeal to test my new theory, I might have gone too far, and sacrificed a human life. I trembled under the sense of my responsibility to my Maker, and to my fellowmen. I seized a glass of water and dashed it in the man's face. The result proved most happy. He recovered in a minute, and knew nothing of what had occurred. Seeing us all stand around he appeared bewildered. I instantly, in as calm a tone as I could command, asked, 'Are you ready to have your tooth extracted?' 'Yes,' he answered, in a hesitating voice. 'It is all over,' I said, pointing to a decayed tooth on the floor. 'No,' he shouted, leaping from his chair. The name of the man who thus for the first time underwent an operation under anaesthesia induced by ether was Eben Frost."