The trail became, as time went on, one of the world's greatest trade routes, under the development of the Spanish Colonies. We have seen how the great Nelson hoped to split these colonies in two by establishing a "Gibraltar" on Lake Nicaragua. A toll of human life has been paid upon this rugged path for every human movement over it. Has it not been said that for every sleeper in the first Panama railway a human being died in the terrors of construction? If it is not true, it is true that of the eight hundred Chinamen who left the Flowery Kingdom to build the line--labourers who knew nothing of the horrors that awaited them in this fever death-bed--many committed suicide. Crowds of labouring peasantry from Ireland found here, too, a more emerald grave, and hordes of negroes filled up with their poor bodies any vacant tombs. Punishment fell upon this railway, for, according to an American writer, it degenerated until its rails "became nothing but two streaks of rust." Another tale of Darien the fateful: Listen, ye sons of Scotia, to the story of one William Paterson, and his New Edinburgh. Not content with having founded the Bank of England, Paterson must fight the great East India Company, and with another enterprising "interloper" he got over-subscribed, a company with a capital of £600,000, and set sail for the isthmus "amid the tears and prayers" of half Scotland. The new settlement was "to hold the key of the world's commerce." "Universal free trade" with all the world was to be maintained; all differences of race and religion were to be annulled in this Utopia. Death, fever, loss, the attacks of the Spaniards and complete disaster--such was the answer of Fate to their enterprise, and of the two thousand trustful souls who left the Clyde in the closing year of the seventeenth century for this desired haven of the Spanish Main, a few hundreds alone returned to tell the tale. Paterson's idea was in reality that of a great empire-builder. It was a magnificent scheme, and only lacked the element of success. England might have possessed another India, and in the New World. The Scotch were fully alive to the position, but the English were stupid, and lost an enormous opportunity.