Modern physiology sets forth as its chief ends: Firstly, the ascertainment of the facts and conditions of cell-life in general. Secondly, in composite organisms, the analysis of the functions of organs into those of the cells of which they are composed. Thirdly, the explication of the processes by which this local cell-life is directly, or indirectly, controlled and brought into relation with the life of the rest of the cells which compose the organism. Fourthly, the investigation of the phenomena of life in general, on the assumption that the physical and chemical processes which take place in the living body are of the same order as those which take place out of it; and that whatever energy is exerted in producing such phenomena is derived from the common stock of energy in the universe. In the fifth place, modern physiology investigates the relation between physical and psychical phenomena, on the assumption that molecular changes in definite portions of nervous matter stand in the relation of necessary antecedents to definite mental states and operations. The work which has been done in each of the directions here indicated is vast, and the accumulation of solid knowledge, which has been effected, is correspondingly great. For the first time in the history of science, physiologists are now in the position to say that they have arrived at clear and distinct, though by no means complete, conceptions of the manner in which the great functions of assimilation, respiration, secretion, distribution of nutriment, removal of waste products, motion, sensation, and reproduction are performed; while the operation of the nervous system, as a regulative apparatus, which influences the origination and the transmission of manifestations of activity, either within itself or in other organs, has been largely elucidated. [Sidenote: Practical value of physiological discovery.]