In 1561 there was issued "A newe booke conteyninge an exortacion to the sicke." The tract ends with the following parody on the nostrums current for the cure of the pestilence: "Take a pond of good hard penaunce, and washe it wel with the water of your eyes, and let it ly a good whyle at youre hert. Take also of the best fyne fayth, hope, charyte yt you can get, a like quantite of al mixed together, your soule even full, and use this confection every day in your lyfe, whiles the plages of God reigneth. Then, take both your handes ful of good workes commaunded of God, and kepe them close in a clene conscience from the duste of vayne glory, and ever as you are able and se necessite so to use them. This medicine was found wryten in an olde byble boke, and it hath been practised and proved true of mani, both men and women" (Collier's _Bib. Account_, i. 74). The wealthy, on an outbreak of the plague, fled from the infected city, as we may learn from Boccaccio, and from Miles Coverdale's translation of Osiander's sermon, "How and whether a Christian man ought to flye the horrible plage of the pestilence," which appeared in 1537. During the plague of London, in 1603, the physicians are asserted by Dekker to have "hid their synodical heads," but this is at all events not wholly true. Thomas Lodge, the poet, was also a graduate in medicine, and in his "Treatise on the Plague"--not the only one published in relation to this epidemic--we are told of his experiences of the plague-stricken city. He gives some good advice in relation to the sanitary measures to be taken for the prevention of the plague. The nature of the regulations devised in the Tudor times to ward off infection may be gathered from the rules laid down at Chester in November, 1574, when "the right Worshipful Sir John Sauage, Knight, maior of the City of Chester had consideracion of the present state of the said cite somewhat visited with what is called the plage, and divisinge the best meanes and orderlie waies he can, with [the advice] of his Bretheren the alderman, Justices of peace within the citie aforesaid (through the goodness of God) to avoid the same hath with such advice, sett forth ordained and appointed (amongst other) the points, articles, clauses, and orders folowing, which he willeth and commandeth all persons to observe and kepe, upon the severall pains theirin contayned: "Imprimis. That no person nor persons who are or shalbe visited with the said sickness, or any other who shall be of there company, shall go abrode out of there houses without license of the alderman of the ward such persons inhabite, And that every person soe licensed to beare openlie in their hands ... three quarters long ... ense ... shall goe abrode out of the ... upon paine that eny person doynge the contrary to be furthwith expulsed out of the said citie.