The natives of the hills through the whole extent of the island are subject to those monstrous wens from the throat which have been observed of the Vallaisans and the inhabitants of other mountainous districts in Europe. It has been usual to attribute this affection to the badness, thawed state, mineral quality, or other peculiarity of the waters; many skilful men having applied themselves to the investigation of the subject. My experience enables me to pronounce without hesitation that the disorder, for such it is though it appears here to mark a distinct race of people (orang-gunong), is immediately connected with the hilliness of the country, and of course, if the circumstances of the water they use contribute thereto, it must be only so far as the nature of the water is affected by the inequality or height of the land. But in Sumatra neither snow nor other congelation is ever produced, which militates against the most plausible conjecture that has been adopted concerning the Alpine goitres. From every research that I have been enabled to make I think I have reason to conclude that the complaint is owing, among the Sumatrans, to the fogginess of the air in the valleys between the high mountains, where, and not on the summits, the natives of these parts reside. I before remarked that, between the ranges of hills, the kabut or dense mist was visible for several hours every morning; rising in a thick, opaque, and well-defined body with the sun, and seldom quite dispersed till afternoon. This phenomenon, as well as that of the wens, being peculiar to the regions of the hills, affords a presumption that they may be connected; exclusive of the natural probability that a cold vapour, gross to a uncommon degree, and continually enveloping the habitations, should affect with tumors the throats of the inhabitants. I cannot pretend to say how far this solution may apply to the case of the goitres, but I recollect it to have been mentioned that the only method of curing the people is by removing them from the valleys to the clear and pure air on the tops of the hills; which seems to indicate a similar source of the distemper to what I have pointed out. The Sumatrans do not appear to attempt any remedy for it, the wens being consistent with the highest health in other respects. DIFFERENCE IN PERSON BETWEEN MALAYS AND OTHER SUMATRANS.